[ 1 ]Structure of the Ebola virus polymerase complex

[ 2 ]Biomimetic Design of Artificial Hybrid Nanocells for Boosted Vascular Regeneration in Ischemic Tissues

[ 3 ]VAMP4/STX8 Mediate the Autophagic Secretion of Mitochondria and Promote TAMs Polarization in HNSCC

[ 4 ]Anti-alcoholism drug disulfiram for targeting glioma energy metabolism using BBB-penetrating delivery of fixed-dose combination

[ 5 ]Enzymatic deamination of the epigenetic nucleoside N6-methyladenosine regulates gene expression

[ 6 ]Enhancer architecture-dependent multilayered transcriptional regulation orchestrates RA signaling-induced early lineage differentiation of ESCs

[ 7 ]Mesopore Controls the Responses of Blood Clot-Immune Complex via Modulating Fibrin Network

[ 8 ]Discovery of Novel GR Ligands toward Druggable GR Antagonist Conformations Identified by MD Simulations and Markov State Model Analysis

[ 9 ]A Dual-Cross-Linked Hydrogel Patch for Promoting Diabetic Wound Healing

[ 10 ]Nuclear Fructose-1,6-Bisphosphate Inhibits Tumor Growth and Sensitizes Chemotherapy by Targeting HMGB1

[ 11 ]Perfluorooctanoic acid (PFOA) exposure affects early embryonic development and offspring oocyte quality via inducing mitochondrial dysfunction

[ 12 ]Targeted manipulation of grain shape genes effectively improves outcrossing rate and hybrid seed production in rice

[ 13 ]AKT1 phosphorylates PRMT7 to promote GLUD1 methylation and gastric cancer progression

[ 14 ]UB2/UB3/TSH4-anchored transcriptional networks regulate early maize inflorescence development in response to simulated shade

[ 15 ]The photomorphogenic repressors BBX28 and BBX29 integrate light and brassinosteroid signaling to inhibit seedling development in Arabidopsis

[ 16 ]High-level secretory production of leghemoglobin in Pichia pastoris through enhanced globin expression and heme biosynthesis

[ 17 ]SNX10-mediated LPS sensing causes intestinal barrier dysfunction via a caspase-5-dependent signaling cascade

[ 18 ]STAT4 activation by leukemia inhibitory factor confers a therapeutic effect on intestinal inflammation

[ 19 ]Zscan4c activates endogenous retrovirus MERVL and cleavage embryo genes

[ 20 ]A distal enhancer maintaining Hoxa1 expression orchestrates retinoic acid-induced early ESCs differentiation

[ 21 ]A novel CREB5/TOP1MT axis confers cisplatin resistance through inhibiting mitochondrial apoptosis in head and neck squamous cell carcinoma

[ 22 ]Fecal transplantation from young zebrafish donors efficiently ameliorates the lipid metabolism disorder of aged recipients exposed to perfluorobutanesulfonate

[ 23 ]Evolution of gene regulatory network of C4 photosynthesis in the genus Flaveria reveals the evolutionary status of C3-C4 intermediate species

[ 24 ]CRISPR-Cas9-based genome-wide screening identified novel targets for treating sorafenib-resistant hepatocellular carcinoma: a cross-talk between FGF21 and the NRF2 pathway

[ 25 ]Paeoniflorin prevents aberrant proliferation and differentiation of intestinal stem cells by controlling C1q release from macrophages in chronic colitis

[ 26 ]Toll-like receptor 10 expression in B cells is negatively correlated with the progression of primary Sjögren's disease

[ 27 ]Sirt7 associates with ELK1 to participate in hyperglycemia memory and diabetic nephropathy via modulation of DAPK3 expression and endothelial inflammation

[ 28 ]The miR156b-GmSPL9d module modulates nodulation by targeting multiple core nodulation genes in soybean

[ 29 ]ZmSPL10/14/26 are required for epidermal hair cell fate specification on maize leaf

[ 30 ]Fungal CFEM effectors negatively regulate a maize wall-associated kinase by interacting with its alternatively spliced variant to dampen resistance

[ 31 ]Rif1 and Hmgn3 regulate the conversion of murine trophoblast stem cells

[ 32 ]Substrate Viscoelasticity Amplifies Distinctions between Transient and Persistent LPS-Induced Signals

[ 33 ]Inhibition of DCLK1 sensitizes resistant lung adenocarcinomas to EGFR-TKI through suppression of Wnt/β-Catenin activity and cancer stemness

[ 34 ]Ciprofloxacin exacerbates dysfunction of smooth muscle cells in a microphysiological model of thoracic aortic aneurysm

[ 35 ]Carbon dots derived from folic acid attenuates osteoarthritis by protecting chondrocytes through NF-κB/MAPK pathway and reprogramming macrophages

[ 36 ]LARP7 ameliorates cellular senescence and aging by allosterically enhancing SIRT1 deacetylase activity

[ 37 ]Rif1 and Hmgn3 Regulate Conversion of Murine Trophoblast Stem Cells

[ 38 ]Bulk and single-cell transcriptome profiling reveal extracellular matrix mechanical regulation of lipid metabolism reprograming through YAP/TEAD4/ACADL axis in hepatocellular carcinoma

[ 39 ]DNMT3a-dermatopontin axis suppresses breast cancer malignancy via inactivating YAP

[ 40 ]Aryl hydrocarbon receptor dependent anti-inflammation and neuroprotective effects of tryptophan metabolites on retinal ischemia/reperfusion injury

[ 41 ]CircRNA MBOAT2 promotes intrahepatic cholangiocarcinoma progression and lipid metabolism reprogramming by stabilizing PTBP1 to facilitate FASN mRNA cytoplasmic export

[ 42 ]circRNA-DURSA regulates trophoblast apoptosis via miR-760-HIST1H2BE axis in unexplained recurrent spontaneous abortion

[ 43 ]The CEL-HYB1 Hybrid Allele Promotes Digestive Enzyme Misfolding and Pancreatitis in Mice

[ 44 ]Structural and Functional Analyses of Type I IFNa Shed Light Into Its Interaction With Multiple Receptors in Fish

[ 45 ]Effect of D-Ala-Ended Peptidoglycan Precursors on the Immune Regulation of Lactobacillus plantarum Strains

[ 46 ]Multi-Omics Analysis for Transcriptional Regulation of Immune-Related Targets Using Epigenetic Data: A New Research Direction

[ 47 ]Circular RNA hsa_circ_0083756 promotes intervertebral disc degeneration by sponging miR-558 and regulating TREM1 expression

[ 48 ]Protein arginine methyltransferase 2 (PRMT2) promotes dextran sulfate sodium-induced colitis by inhibiting the SOCS3 promoter via histone H3R8 asymmetric dimethylation

[ 49 ]LXR activation potentiates sorafenib sensitivity in HCC by activating microRNA-378a transcription

[ 50 ]Splicing factor arginine/serine-rich 8 promotes multiple myeloma malignancy and bone lesion through alternative splicing of CACYBP and exosome-based cellular communication

[ 51 ]MIR22HG inhibits breast cancer progression by stabilizing LATS2 tumor suppressor

[ 52 ]Chronic stress promotes breast carcinoma metastasis by accumulating myeloid-derived suppressor cells through activating β-adrenergic signaling

[ 53 ]miRNA novel_268 targeting NlABCG3 is involved in nitenpyram and clothianidin resistance in Nilaparvata lugens

[ 54 ]Identification and expression analysis of G protein-coupled receptors in the cotton aphid, Aphis gossypii Glover

[ 55 ]Odorant binding protein 3 is associated with nitenpyram and sulfoxaflor resistance in Nilaparvata lugens

[ 56 ]TRIM16 attenuates TDP43-mediated oxidative injury by coordinating Nrf2 activation and TFR1 autophagic degradation

[ 57 ]Filgotinib inhibits METTL3-mediated m6A of EIF3A by targeting ERG-TBP to suppress PDAC progression JAK-STAT3-independently

[ 58 ]Bioaccumulation, metabolism and endocrine-reproductive effects of metolachlor and its S-enantiomer in adult zebrafish (Danio rerio)

[ 59 ]Expanded Expression Landscape and Prioritization of Circular RNAs in Mammals

[ 60 ]A positive feedback loop between FGR and p65 sustains satellite glial cell activation and chronic neuropathic pain

[ 61 ]Effects of cadmium toxicity on diploid wheat (Triticum urartu) and the molecular mechanism of the cadmium response

[ 62 ]Discovery of a Novel Androgen Receptor Antagonist Manifesting Evidence to Disrupt the Dimerization of the Ligand-Binding Domain via Attenuating the Hydrogen-Bonding Network Between the Two Monomers

[ 63 ]A HD-ZIP III gene, PtrHB4, is required for interfascicular cambium development in Populus

[ 64 ]A comparative study of vestibular improvement and gastrointestinal effect of betahistine and gastrodin in mice

[ 65 ]Stilbene B10 induces apoptosis and tumor suppression in lymphoid Raji cells by BTK-mediated regulation of the KRAS/HDAC1/EP300/PEBP1 axis

[ 66 ]Riboflavin mediates m6A modification targeted by miR408, promoting early somatic embryogenesis in longan

[ 67 ]TRIPTYCHON-LIKE regulates aspects of both fruit flavor and color in citrus

[ 68 ]Mobility of FLOWERING LOCUS T protein as a systemic signal in trifoliate orange and its low accumulation in grafted juvenile scions

[ 69 ]Ginkgolide A targets forkhead box O1 to protect against lipopolysaccharide-induced septic cardiomyopathy

[ 70 ]Discovery of a novel nonsteroidal selective glucocorticoid receptor modulator by virtual screening and bioassays

[ 71 ]The development, reproduction and P450 enzyme of the white-backed planthopper, Sogatella furcifera (Hemiptera: Delphacidae) under the sublethal concentrations of clothianidin

[ 72 ]A xylem-produced peptide PtrCLE20 inhibits vascular cambium activity in Populus

[ 73 ]Liquiritigenin Inhibits Lipid Accumulation in 3T3-L1 Cells via mTOR-Mediated Regulation of the Autophagy Mechanism

[ 74 ]Uncovering the role of transient receptor potential channels in pterygium: a machine learning approach

[ 75 ]Hsa_Circ_0001860 Promotes Smad7 to Enhance MPA Resistance in Endometrial Cancer via miR-520h

[ 76 ]PLXNC1: A Novel Potential Immune-Related Target for Stomach Adenocarcinoma

[ 77 ]Suppression of microglial activation and monocyte infiltration ameliorates cerebellar hemorrhage induced-brain injury and ataxia

[ 78 ]Cyclocarya paliurus Reprograms the Flavonoid Biosynthesis Pathway Against Colletotrichum fructicola.

[ 79 ]Empagliflozin adjunct with metformin for the inhibition of hepatocellular carcinoma progression: Emerging approach for new application

[ 80 ]PLA2G10 incorporated in exosomes could be diagnostic and prognostic biomarker for non-small cell lung cancer

[ 81 ]miR-486-3p mediates hepatocellular carcinoma sorafenib resistance by targeting FGFR4 and EGFR

[ 82 ]Development of an Aerobic Glycolysis Index for Predicting the Sorafenib Sensitivity and Prognosis of Hepatocellular Carcinoma

[ 83 ]Chromatin Accessibility Regulates Gene Expression and Correlates With Tumor-Infiltrating Immune Cells in Gastric Adenocarcinoma

[ 84 ]The Cross-Resistance Pattern and the Metabolic Resistance Mechanism of Acetamiprid in the Brown Planthopper, Nilaparvata lugens (Stål)

[ 85 ]LSD1 downregulates p21 expression in vascular smooth muscle cells and promotes neointima formation

[ 86 ]Mechanisms of Senescence-Related NKG2D Ligands Release and Immune Escape Induced by Chemotherapy in Neuroblastoma Cells

[ 87 ]Ferroptosis due to Cystathionine γ Lyase/Hydrogen Sulfide Downregulation Under High Hydrostatic Pressure Exacerbates VSMC Dysfunction

[ 88 ]Curcumin-driven reprogramming of the gut microbiota and metabolome ameliorates motor deficits and neuroinflammation in a mouse model of Parkinson’s disease

[ 89 ]Construction of Exosomes that Overexpress CD47 and Evaluation of Their Immune Escape

[ 90 ]Integrating Transcriptomic and ChIP-Seq Reveals Important Regulatory Regions Modulating Gene Expression in Myometrium during Implantation in Pigs

[ 91 ]ELAC2 Functions as a Key Gene in the Early Development of Placental Formation Based on WGCNA

[ 92 ]The Receptor-Like Kinase AtVRLK1 Regulates Secondary Cell Wall Thickening

[ 93 ]Tanshinone IIA Activates Nuclear Factor-Erythroid 2-Related Factor 2 to Restrain Pulmonary Fibrosis via Regulation of Redox Homeostasis and Glutaminolysis

[ 94 ]Levistolide A Inhibits PEDV Replication via Inducing ROS Generation

[ 95 ]Azilsartan Suppresses Osteoclastogenesis and Ameliorates Ovariectomy-Induced Osteoporosis by Inhibiting Reactive Oxygen Species Production and Activating Nrf2 Signaling

[ 96 ]Ligustrazine Alleviate Acute Lung Injury Through Suppressing Pyroptosis and Apoptosis of Alveolar Macrophages

[ 97 ]Elevated expression of macrophage MERTK exhibits profibrotic effects and results in defective regulation of efferocytosis function in pulmonary fibrosis

[ 98 ]Pepper previously infested by MED facilitates settling and oviposition by MEAM1 of the Bemisia tabaci species complex

[ 99 ]Genistein Regulates Lipid Metabolism via Estrogen Receptor β and Its Downstream Signal Akt/mTOR in HepG2 Cells

[ 100 ]Hsa_circ_0087352 promotes the inflammatory response of macrophages in abdominal aortic aneurysm by adsorbing hsa-miR-149-5p