[ 1 ]Thromboxane receptor activation in dendritic cells mitigates sepsis by suppressing S100a8/a9-mediated neutrophil recruitment

[ 2 ]Sensing endoplasmic reticulum redox state by ethylene receptors

[ 3 ]FOXA2 drives lineage plasticity and KIT pathway activation in neuroendocrine prostate cancer

[ 4 ]Functional divergence of two ethylene receptor subfamilies in calcium permeability

[ 5 ]Glioblastoma-secreted C1QL1 orchestrates tumor microtube expansion and neural synaptic pruning to drive malignant synapse formation and recurrence

[ 6 ]SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target

[ 7 ]Gynostemma pentaphyllum-derived extracellular vesicles alleviate skin aging by destabilizing STING

[ 8 ]In vivo profiling of astrocyte secretome reveals brain-region specific regulatory networks in a mouse model of amyloid pathology

[ 9 ]Bafetinib enhances anti-tumor immunity by activating the NLRP3 inflammasome in macrophage

[ 10 ]Engineered dCas12f1-SAM enables robust transcriptional activation and gain-of-function screening in primary human cells

[ 11 ]Metabolic characterization of the tumor microenvironment orchestrates therapeutic strategies and clinical outcomes in pancreatic cancer

[ 12 ]Enhancing soluble sugar accumulation in banana (Musa acuminata) through 5-azacytidine-mediated reinforcement of starch degradation involving DNA methylation-dependent and independent pathways

[ 13 ]Targeting myofibroblast copper vulnerability reverses pulmonary fibrosis via METTL3-directed STAT6 m6A driving cuproptosis

[ 14 ]Maxillary palp odorant-binding proteins as key mediators of bitter taste and molecular targets for cockroach control

[ 15 ]Phosphoglycerate dehydrogenase activates PKM2 to phosphorylate histone H3T11 and attenuate cellular senescence

[ 16 ]The landscape of tissue-resident microbiota across normal, polyp, and colorectal cancer tissues

[ 17 ]Target-stabilized base editors enable robust high-fidelity RNA editing

[ 18 ]A versatile CRISPR-associated transposases-mediated toolkit for transcriptional regulation library

[ 19 ]A ROS-responsive core–shell microneedle platform integrating sonodynamic gas antibacterial therapy and modulating immunity for diabetic wound healing

[ 20 ]Ginseng-derived vesicle-like nanoparticles deliver pgi-MIR6136a-p3 for sepsis therapy via ELF3/NF-κB signaling axis

[ 21 ]Gut microenvironment-responsive copper selenide/disulfiram/eudragit® L100-55 nanoflowers alleviate chronic pancreatitis via the inhibition of pyroptosis and pancreatic stellate cell activation

[ 22 ]Microglia-Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis-Associated Encephalopathy

[ 23 ]N4-acetylcytidine in LncRNA Gm26917 Promotes Translation in Female Germline Stem Cells by Recruiting Ribosomal Protein mRNA via EEF1A1

[ 24 ]Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling

[ 25 ]IGF-1 Deficiency Serves as an Integrated Biomarker Pathogenic Driver and Predictor in Poor Ovarian Response

[ 26 ]Machine learning–directed massively parallel programmable nucleic acid amplification

[ 27 ]mTOR-NAA10-C7orf50 axis senses nutritional status to coordinate ribosome biogenesis and autophagy

[ 28 ]GSDME acts as an epigenetic modifier to promote melanoma development via centriole biogenesis regulator PLK4

[ 29 ]Endothelial USP2a-METTL16 loop potentiates IL-6 signaling via m6A-mediated IL-6R stabilization in pulmonary vascular remodeling

[ 30 ]Single-cell and tissue transcriptomes unveil factors regulating vein initiation and development in grass leaf primordia

[ 31 ]N-acetylcysteine-functionalized biodegradable polysaccharide hydrogel patches for the repair of acute liver injury

[ 32 ]Microneedle-based delivery of cell membrane vesicles as IL-17RA decoys for Psoriasis treatment

[ 33 ]Histone H3K27 methyltransferase EZH2 regulates apoptotic and inflammatory responses in sepsis-induced AKI

[ 34 ]Genetically engineered nanovesicles mobilize synergistic antitumor immunity by ADAR1 silence and PDL1 blockade

[ 35 ]ZRANB1 promotes cell proliferation and lymph node metastasis through SF3B3-mediated alternative splicing of CHEK2 in urothelial bladder cancer

[ 36 ]CHML promotes liver cancer metastasis by facilitating Rab14 recycle

[ 37 ]DHCR24 Deficiency Drives Age-Related Meibomian Gland Dysfunction by Regulating Lipid Metabolic Imbalance and Cytosolic mtDNA-Induced cGAS-STING Activation

[ 38 ]Targeting IL-1α Sensitizes HNSCC to PDT by Reversing Hypoxia and NF-κB-Driven Oxidative Stress Resistance

[ 39 ]Grass carp reovirus VP35 hijacks DHX15 into phase-separated inclusion bodies to evade host antiviral immunity

[ 40 ]Kisspeptin/GPR54 signaling restricts antiviral innate immune response through regulating calcineurin phosphatase activity

[ 41 ]GPR35 protects against reperfusion injury in ischemic stroke by binding with the CR2 domain of Raf1

[ 42 ]Accumulated cholesterol protects tumours from elevated lipid peroxidation in the microenvironment

[ 43 ]Oligopeptides from Gynura divaricata Improve Glycemic Control via Inhibition of Gluconeogenesis and Gut-Brain Axis Regulation

[ 44 ]Platelets as immune sensors: monitoring immune dynamics and diagnosing disease states across multiple disorders

[ 45 ]Hierarchical Piezoelectric Conduit Coordinates Bioelectric Cues and MicroRNA Regulation for Functional Neurological Regeneration

[ 46 ]Structural characterization of a novel glucan from rice bran, evaluation of its potential antioxidant and anti-allergy activities

[ 47 ]Single-cell mapping of tumor-driven macrophage reprogramming via ETV4-MC1R underlies immunotherapy resistance in colorectal cancer

[ 48 ]Developmental defects and potential mechanisms in F1 generation of parents exposed to difenoconazole at different life stages of zebrafish (Danio rerio)

[ 49 ]Gut microbiota modulate radiotherapy-associated antitumor immune responses against hepatocellular carcinoma Via STING signaling

[ 50 ]Azacytidine-induced hypomethylation delays senescence and coloration in harvested strawberries by stimulating antioxidant enzymes and modulating abscisate metabolism to minimize anthocyanin overproduction

[ 51 ]Efficient gene editing through an intronic selection marker in cells

[ 52 ]The UDPase ENTPD5 regulates ER stress-associated renal injury by mediating protein N-glycosylation

[ 53 ]Exercise Attenuates Aortic Dissection Via PDE5A-Mediated Inhibition of Vascular Smooth Muscle Cell Phenotypic Switch

[ 54 ]Promoter Binding and Nuclear Retention Features of Zebrafish IRF Family Members in IFN Response

[ 55 ]Nelumbo nucifera extract alleviates UVB-induced hyperpigmentation via NOX4-mediated AMPK-YAP-ATG5 signaling pathway

[ 56 ]Genome-wide identification of the NAC transcription factors family and regulation of metabolites under salt stress in Isatis indigotica

[ 57 ]Intra-articular treatment of temporomandibular joint osteoarthritis by injecting actively-loaded meloxicam liposomes with dual-functions of anti-inflammation and lubrication

[ 58 ]Engineering a gut synthetic microbial community to enhance protein bioconversion from organic wastes by black soldier fly larvae

[ 59 ]Histone H3K27 acetylation of slc25a4 mediates triclocarban-induced transgenerational developmental toxicity in zebrafish (Danio rerio) at subthreshold exposure

[ 60 ]A Drug-Free Polysaccharide Hydrogel Encapsulating Iron Oxide Nanoparticles against Postoperative Tumor Recurrence and Metastasis

[ 61 ]Panaxatriol saponin ameliorates myocardial infarction-induced cardiac fibrosis by targeting Keap1/Nrf2 to regulate oxidative stress and inhibit cardiac-fibroblast activation and proliferation

[ 62 ]Single-cell transcriptomics reveals the cell fate transitions of human dopaminergic progenitors derived from hESCs

[ 63 ]Function of Foxl2 and Dmrt1 proteins during gonadal differentiation in the olive flounder Paralichthys olivaceus

[ 64 ]A sensitive double antibodies sandwich ELISA for the diagnosis and therapeutic evaluation of cervical cancer

[ 65 ]Arabidopsis HOPS subunit VPS41 carries out plant-specific roles in vacuolar transport and vegetative growth

[ 66 ]MitoQ attenuates maternal immune activation–induced mitochondrial and ER stress programs and ameliorates psychiatric-like behavioral deficits

[ 67 ]Fuzheng Kang-Ai inhibits NSCLC cell proliferation via regulating hsa_circ_0048091/hsa-miR-378g/ARRDC3 pathway

[ 68 ]A single-nucleus and spatial transcriptomic atlas of poplar leaves reveals the regulation of leaf polarity and cuticle deposition

[ 69 ]Suppression of LRRC41-mediated oncogenicity in hepatocellular carcinoma via USP7-targeted small molecule inhibitors

[ 70 ]FASN inactivation-induced progranulin (GRN) expression promotes lysosome-dependent cell death to suppress leukemogenesis

[ 71 ]Spatial and single-cell transcriptomics reveals senescence-associated changes in MIA-induced ASD male mouse brain

[ 72 ]Metrnl Alleviates Lipid Accumulation by Modulating Mitochondrial Homeostasis in Diabetic Nephropathy

[ 73 ]Aging Triggers an Intestinal Energy Crisis and HDL3 Deficiency Disrupting Gut–Liver Axis Homeostasis

[ 74 ]Mass Spectrometry Imaging of Lipids in the Scent Glands of Muskrat (Ondatra zibethicus) in Different Reproductive Statuses

[ 75 ]Integration of physiological and metabolomic profiles to elucidate the regulatory mechanisms underlying the stimulatory effect of melatonin on astaxanthin and lipids coproduction in Haematococcus pluvialis under inductive stress conditions

[ 76 ]Identifying novel biomarkers for systemic lupus erythematosus associated with macrophage activation syndrome

[ 77 ]Moxibustion delays ovarian aging by regulating mitochondrial biogenesis and improving oocyte quality

[ 78 ]Establishment of Immortalized Yak Ruminal Epithelial Cell Lines by Lentivirus-Mediated SV40T and hTERT Gene Transduction

[ 79 ]Nicandra physalodes Extract Exerts Antiaging Effects in Multiple Models and Extends the Lifespan of Caenorhabditis elegans via DAF-16 and HSF-1

[ 80 ]Discovery of Novel MDH2 Inhibitor 28i by Secondary Development of Glibenclamide with Potent Antiaging Activities

[ 81 ]Suppression Probe Enrichment for Highly Sensitive and Multiplexed Detection of RAS Mutations in Colorectal Cancer

[ 82 ]PM2.5 exposure triggers cell death through lysosomal membrane permeabilization and leads to ferroptosis insensitivity via the autophagy dysfunction/p62-KEAP1-NRF2 activation in neuronal cells

[ 83 ]MYSM1 induces apoptosis and sensitizes TNBC cells to cisplatin via RSK3–phospho-BAD pathway

[ 84 ]Sex-specific regulation of SLC39A11 in the murine liver

[ 85 ]Development of species-specific ERA-lateral flow strip assays to authenticate duck, donkey, and sheep/goat ingredients in processed meat products

[ 86 ]GCDCA promotes hepatocellular carcinoma progression through S1PR2/PI3K/AKT-mediated polarization of M2-type macrophages

[ 87 ]Quercetin attenuates skin inflammation and fibrosis in systemic sclerosis by targeting the RELA/c-Jun axis to suppress th17 cell responses

[ 88 ]FUT8 reprograms glycolytic metabolism to promote PKM2 lactylation and drive clear cell renal cell carcinoma progression

[ 89 ]HSP70/TLR2 Orchestrates Melanocyte Ferroptosis in the Onset of Vitiligo

[ 90 ]A microfluidic cell chip for virus isolation via rapid screening for permissive cells

[ 91 ]Isosteviol Sodium Exerts Anti-Colitic Effects on BALB/c Mice with Dextran Sodium Sulfate-Induced Colitis Through Metabolic Reprogramming and Immune Response Modulation

[ 92 ]Sirtuin 5‐mediated desuccinylation of PRDX6 inhibits ferroptosis and alleviates sepsis-associated acute kidney injury

[ 93 ]The bHLH transcription factor IBL1 fine-tunes growth and development via restraining cell elongation/expansion in Arabidopsis

[ 94 ]Reciprocal regulation between autism risk gene POGZ and circadian clock

[ 95 ]Nuclear Receptors as Lethal Targets in the White-Backed Planthopper via RNAi and Nanocarrier Delivery

[ 96 ]Recovery of Behavioral Impairments in F1 Offspring of Zebrafish (Danio rerio) Induced by Parental Imidacloprid Exposure Linked to Attenuation of Disruptions in Visual and Circadian Systems

[ 97 ]Daidzein Activates Akt Pathway to Promote the Proliferation of Female Germline Stem Cells through Upregulating Clec11a

[ 98 ]Gallic acid ameliorates calcium oxalate crystal-induced renal injury via upregulation of Nrf2/HO-1 in the mouse model of stone formation

[ 99 ]MCC‐135 Exerts Antiepileptic and Neuroprotective Effects by Downregulating NCX1 Expression to Decrease Intracellular Calcium Overload in the Hippocampus

[ 100 ]Integrated analysis of gut microbiota and transcriptional responses reveals thermotolerance mechanisms in Arma chinensis