[ 1 ]NLR surveillance of pathogen interference with hormone receptors induces immunity

[ 2 ]Olfactory sensory experience regulates gliomagenesis via neuronal IGF1

[ 3 ]Opioid-induced fragile-like regulatory T cells contribute to withdrawal

[ 4 ]A bacterial phospholipid phosphatase inhibits host pyroptosis by hijacking ubiquitin

[ 5 ]Cholesterylation of Smoothened is a calcium-accelerated autoreaction involving an intramolecular ester intermediate

[ 6 ]Long non-coding RNA LINC00680 functions as a ceRNA to promote esophageal squamous cell carcinoma progression through the miR-423-5p/PAK6 axis

[ 7 ]Lateral plate mesoderm cell-based organoid system for NK cell regeneration from human pluripotent stem cells

[ 8 ]Biomimetic Design of Artificial Hybrid Nanocells for Boosted Vascular Regeneration in Ischemic Tissues

[ 9 ]Comprehensive Analysis of Fibroblast Activation Protein (FAP) Expression in Interstitial Lung Diseases (ILDs)

[ 10 ]Circ3823 contributes to growth, metastasis and angiogenesis of colorectal cancer: involvement of miR-30c-5p/TCF7 axis

[ 11 ]Cancer cell-derived exosomal circUSP7 induces CD8+ T cell dysfunction and anti-PD1 resistance by regulating the miR-934/SHP2 axis in NSCLC

[ 12 ]The OsFTIP6-OsHB22-OsMYBR57 module regulates drought response in rice

[ 13 ]A mouse-adapted CVA6 strain exhibits neurotropism and triggers systemic manifestations in a novel murine model

[ 14 ]N4-acetylcytidine regulates the replication and pathogenicity of enterovirus 71

[ 15 ]KLF4 inhibits early neural differentiation of ESCs by coordinating specific 3D chromatin structure

[ 16 ]Anti-alcoholism drug disulfiram for targeting glioma energy metabolism using BBB-penetrating delivery of fixed-dose combination

[ 17 ]Fabrication, bacteriostasis and osteointegration properties researches of the additively-manufactured porous tantalum scaffolds loading vancomycin

[ 18 ]Cholinergic Neuron Targeting Nanosystem Delivering Hybrid Peptide for Combinatorial Mitochondrial Therapy in Alzheimer’s Disease

[ 19 ]The SWI/SNF chromatin remodeling factor DPF3 regulates metastasis of ccRCC by modulating TGF-β signaling

[ 20 ]Identification of oleoylethanolamide as an endogenous ligand for HIF-3α

[ 21 ]High-resolution silkworm pan-genome provides genetic insights into artificial selection and ecological adaptation

[ 22 ]IL6 supports long-term expansion of hepatocytes in vitro

[ 23 ]Independently evolved viral effectors convergently suppress DELLA protein SLR1-mediated broad-spectrum antiviral immunity in rice

[ 24 ]PRDM1/BLIMP1 induces cancer immune evasion by modulating the USP22-SPI1-PD-L1 axis in hepatocellular carcinoma cells

[ 25 ]Conscription of Immune Cells by Light-Activatable Silencing NK-Derived Exosome (LASNEO) for Synergetic Tumor Eradication

[ 26 ]Functionalized Macrophage Exosomes with Panobinostat and PPM1D-siRNA for Diffuse Intrinsic Pontine Gliomas Therapy

[ 27 ]Group 3 Innate Lymphoid Cells Protect the Host from the Uropathogenic Escherichia coli Infection in the Bladder

[ 28 ]Matrix stiffness exacerbates the proinflammatory responses of vascular smooth muscle cell through the DDR1-DNMT1 mechanotransduction axis

[ 29 ]Colon-Targeted Adhesive Hydrogel Microsphere for Regulation of Gut Immunity and Flora

[ 30 ]CeO2 nanohybrid as a synergist for insecticide resistance management

[ 31 ]Modulation of MRSA virulence gene expression by the wall teichoic acid enzyme TarO

[ 32 ]Neuraminidase 1 promotes renal fibrosis development in male mice

[ 33 ]Inhibition of ALKBH5 attenuates I/R-induced renal injury in male mice by promoting Ccl28 m6A modification and increasing Treg recruitment

[ 34 ]Nucleus accumbens circuit disinhibits lateral hypothalamus glutamatergic neurons contributing to morphine withdrawal memory in male mice

[ 35 ]Stringent response ensures the timely adaptation of bacterial growth to nutrient downshift

[ 36 ]Glycolysis drives STING signaling to facilitate dendritic cell antitumor function

[ 37 ]Somatic variations led to the selection of acidic and acidless orange cultivars

[ 38 ]A YAP/TAZ-CD54 axis is required for CXCR2−CD44− tumor-specific neutrophils to suppress gastric cancer

[ 39 ]Ru(II)-modified TiO2 nanoparticles for hypoxia-adaptive photo-immunotherapy of oral squamous cell carcinoma

[ 40 ]Modulating cancer-stroma crosstalk by a nanoparticle-based photodynamic method to pave the way for subsequent therapies

[ 41 ]Collaborative Design of MgO/FeOx Nanosheets on Titanium: Combining Therapy with Regeneration

[ 42 ]A Human-Specific De Novo Gene Promotes Cortical Expansion and Folding

[ 43 ]Neuroinflammation inhibition by small-molecule targeting USP7 noncatalytic domain for neurodegenerative disease therapy

[ 44 ]Oral zero-valent-molybdenum nanodots for inflammatory bowel disease therapy

[ 45 ]Gene interfered-ferroptosis therapy for cancers

[ 46 ]A longitudinal sampling study of transcriptomic and epigenetic profiles in patients with thrombocytopenia syndrome

[ 47 ]A smart multiantenna gene theranostic system based on the programmed assembly of hypoxia-related siRNAs

[ 48 ]The folate cycle enzyme MTHFD2 induces cancer immune evasion through PD-L1 up-regulation

[ 49 ]Translocation of vaginal microbiota is involved in impairment and protection of uterine health

[ 50 ]Role of Hakai in m6A modification pathway in Drosophila

[ 51 ]A novel active transposon creates allelic variation through altered translation rate to influence protein abundance

[ 52 ]The deubiquitinating enzyme 13 retards non-alcoholic steatohepatitis via blocking inactive rhomboid protein 2-dependent pathway

[ 53 ]Injectable self-healing hydrogel with siRNA delivery property for sustained STING silencing and enhanced therapy of intervertebral disc degeneration

[ 54 ]Multi-scale analysis of nickel ion tolerance mechanism for thermophilic Sulfobacillus thermosulfidooxidans in bioleaching

[ 55 ]Boron contributes to excessive aluminum tolerance in trifoliate orange (Poncirus trifoliata (L.) Raf.) by inhibiting cell wall deposition and promoting vacuole compartmentation

[ 56 ]Bacillus coagulans XY2 ameliorates copper-induced toxicity by bioadsorption, gut microbiota and lipid metabolism regulation

[ 57 ]Characterizing the obesogenic and fatty liver-inducing effects of Acetyl tributyl citrate (ATBC) plasticizer using both in vivo and in vitro models

[ 58 ]Embedded CRISPRi Enhances Gene-Silencing Efficiency in Drosophila

[ 59 ]Identification of TaGL1-B1 gene controlling grain length through regulation of jasmonic acid in common wheat

[ 60 ]A natural promoter variation of SlBBX31 confers enhanced cold tolerance during tomato domestication

[ 61 ]A nitrogen fixing symbiosis-specific pathway required for legume flowering

[ 62 ]Using Fe biofortification strategies to reduce both Ni concentration and oral bioavailability for rice with high Ni

[ 63 ]The gut microbiome promotes arsenic metabolism and alleviates the metabolic disorder for their mammal host under arsenic exposure

[ 64 ]Effects of various Fe compounds on the bioavailability of Pb contained in orally ingested soils in mice: Mechanistic insights and health implications

[ 65 ]Single-cell transcriptome atlas reveals developmental trajectories and a novel metabolic pathway of catechin esters in tea leaves

[ 66 ]A novel miR167a-OsARF6-OsAUX3 module regulates grain length and weight in rice

[ 67 ]Nuclear translocation of OsMFT1 that is impeded by OsFTIP1 promotes drought tolerance in rice

[ 68 ]Engineering of efficiency-enhanced Cas9 and base editors with improved gene therapy efficacies

[ 69 ]A Mechano-Feedback Loop Orchestrated by SUN1/2 Governs Cellular Mechanoadaptation via Lamina-Associated Domain Remodeling

[ 70 ]MaNAC029 modulates ethylene biosynthesis and fruit quality and undergoes MaXB3-mediated proteasomal degradation during banana ripening

[ 71 ]Local immune dysregulation and subsequent inflammatory response contribute to pulmonary edema caused by Enterovirus infection in mice

[ 72 ]Selective sorting and secretion of hY4 RNA fragments into extracellular vesicles mediated by methylated YBX1 to promote lung cancer progression

[ 73 ]A novel protein encoded by circHNRNPU promotes multiple myeloma progression by regulating the bone marrow microenvironment and alternative splicing

[ 74 ]Targeting ZFP64/GAL-1 axis promotes therapeutic effect of nab-paclitaxel and reverses immunosuppressive microenvironment in gastric cancer

[ 75 ]CircSCAP interacts with SF3A3 to inhibit the malignance of non-small cell lung cancer by activating p53 signaling

[ 76 ]Tetrahedron supported CRISPR/Cas13a cleavage for electrochemical detection of circular RNA in bladder cancer

[ 77 ]Precise gene delivery systems with detachable albumin shell remodeling dysfunctional microglia by TREM2 for treatment of Alzheimer's disease

[ 78 ]HSP70 attenuates compression-induced apoptosis of nucleus pulposus cells by suppressing mitochondrial fission via upregulating the expression of SIRT3

[ 79 ]The tetratricopeptide repeat protein OsTPR075 promotes heading by regulating florigen transport in rice

[ 80 ]The tomato OST1–VOZ1 module regulates drought-mediated flowering

[ 81 ]The type-B response regulators ARR10, ARR12, and ARR18 specify the central cell in Arabidopsis

[ 82 ]AdMSC-derived exosomes alleviate acute lung injury via transferring mitochondrial component to improve homeostasis of alveolar macrophages

[ 83 ]Loss of MLKL ameliorates liver fibrosis by inhibiting hepatocyte necroptosis and hepatic stellate cell activation

[ 84 ]Antibiotic Azithromycin inhibits brown/beige fat functionality and promotes obesity in human and rodents

[ 85 ]UBR5 promotes tumor immune evasion through enhancing IFN-γ-induced PDL1 transcription in triple negative breast cancer.

[ 86 ]Magnetism-mediated targeting hyperthermia-immunotherapy in “cold” tumor with CSF1R inhibitor

[ 87 ]HBx represses WDR77 to enhance HBV replication by DDB1-mediated WDR77 degradation in the liver

[ 88 ]Activating AhR alleviates cognitive deficits of Alzheimer's disease model mice by upregulating endogenous Aβ catabolic enzyme Neprilysin

[ 89 ]hnRNPU in Sertoli cells cooperates with WT1 and is essential for testicular development by modulating transcriptional factors Sox8/9

[ 90 ]Generation of triacyl lipopeptide-modified glycoproteins by metabolic glycoengineering as the neoantigen to boost anti-tumor immune response

[ 91 ]Receptor-like cytoplasmic kinases PBL34/35/36 are required for CLE peptide-mediated signaling to maintain shoot apical meristem and root apical meristem homeostasis in Arabidopsis

[ 92 ]Epigenetic activation of the elongator complex sensitizes gallbladder cancer to gemcitabine therapy

[ 93 ]Complementary and Synergistic Design of Bi-Layered Double Hydroxides Modified Magnesium Alloy toward Multifunctional Orthopedic Implants

[ 94 ]Ca Minerals and Oral Bioavailability of Pb, Cd, and As from Indoor Dust in Mice: Mechanisms and Health Implications

[ 95 ]TCF7L2 acts as a molecular switch in midbrain to control mammal vocalization through its DNA binding domain but not transcription activation domain

[ 96 ]p53 directly downregulates the expression of CDC20 to exert anti-tumor activity in mantle cell lymphoma

[ 97 ]The AGPS regulatory variant rs113671272 confers esophageal squamous cell carcinoma susceptibility through allele-specific MEIS3 binding and NF-κB activation in Chinese populations

[ 98 ]HDAC11 negatively regulates antifungal immunity by inhibiting Nos2 expression via binding with transcriptional repressor STAT3

[ 99 ]Mussel-inspired collagen-hyaluronic acid composite scaffold with excellent antioxidant properties and sustained release of a growth factor for enhancing diabetic wound healing

[ 100 ]β-Ionone causes endocrine disruption, hyperpigmentation and hypoactivity in zebrafish early life stages