Human pluripotent stem-cell-derived islets ameliorate diabetes in non-human primates

Journal:NATURE MEDICINE|DOI:10.1038/s41591-021-01645-7|IF:87.24

Unleashing the potential of bimetallic nanobomb-mediated STING pathway to enhance bispecific T-cell engager against colorectal cancer photo-immunotherapy

Journal:Signal Transduction and Targeted Therapy|DOI:10.1038/s41392-026-02596-6|IF:81.2

A biosafe mouse model for SARS-CoV-2 infection that more realistically simulates COVID-19 symptoms

Journal:Signal Transduction and Targeted Therapy|DOI:10.1038/s41392-026-02640-5|IF:81.2

Investigating the effects and underlying mechanisms of glycosylation sites on the immunogenicity of COVID-19 vaccines

Journal:Signal Transduction and Targeted Therapy|DOI:10.1038/s41392-026-02751-z|IF:81.2

Disrupting SOX2 self-association and condensate formation to overcome chemotherapeutic drug resistance in lung squamous cell carcinoma

Journal:Signal Transduction and Targeted Therapy|DOI:10.1038/s41392-026-02696-3|IF:81.2

Conductive coordination nanozyme prodrugs precisely trigger pyroptosis, cuproptosis and ferroptosis for in situ cancer vaccination

Journal:Signal Transduction and Targeted Therapy|DOI:10.1038/s41392-026-02607-6|IF:81.2

Thromboxane receptor activation in dendritic cells mitigates sepsis by suppressing S100a8/a9-mediated neutrophil recruitment

Journal:Signal Transduction and Targeted Therapy|DOI:10.1038/s41392-026-02592-w|IF:81.2

Targeting ZMIZ1 induces differentiation in acute myeloid leukemia via chromatin remodeling

Journal:Signal Transduction and Targeted Therapy|DOI:10.1038/s41392-026-02766-6|IF:81.2

BMX inhibition overcomes small cell lung cancer chemoresistance by stabilizing E2F1 via ERK1/2-Cyclin D1/CDK4/6 axis

Journal:Signal Transduction and Targeted Therapy|DOI:10.1038/s41392-026-02644-1|IF:81.2

Molecular mechanism of cholesterol-dependent membrane fusion in SARS-CoV-2 entry

Journal:Signal Transduction and Targeted Therapy|DOI:10.1038/s41392-026-02573-z|IF:81.2

VCPIP1 drives diabetic cardiomyopathy by deubiquitinating AMPKγ1 and preventing AMPKα-γ subunit assembly in cardiomyocytes

Journal:Signal Transduction and Targeted Therapy|DOI:10.1038/s41392-026-02701-9|IF:81.2

NLR surveillance of pathogen interference with hormone receptors induces immunity

Journal:NATURE|DOI:10.1038/s41586-022-05529-9|IF:69.5

Structure of the Ebola virus polymerase complex

Journal:NATURE|DOI:10.1038/s41586-022-05271-2|IF:69.5

Olfactory sensory experience regulates gliomagenesis via neuronal IGF1

Journal:NATURE|DOI:10.1038/s41586-022-04719-9|IF:69.5

Brown-fat-mediated tumour suppression by cold-altered global metabolism

Journal:NATURE|DOI:10.1038/s41586-022-05030-3|IF:69.5

Inhibition of ASGR1 decreases lipid levels by promoting cholesterol excretion

Journal:NATURE|DOI:10.1038/s41586-022-05006-3|IF:69.5

USP14-regulated allostery of the human proteasome by time-resolved cryo-EM

Journal:NATURE|DOI:10.1038/s41586-022-04671-8|IF:69.5

Optogenetic control of RNA function and metabolism using engineered light-switchable RNA-binding proteins

Journal:NATURE BIOTECHNOLOGY|DOI:10.1038/s41587-021-01112-1|IF:68.16