Clonidine HCl盐酸可乐定 α2-adrenoceptor激动剂|CAS 4205-91-8（53631ES）

Clonidine hydrochloride (Clonidine HCl)，又称盐酸可乐定，是α2-adrenoceptor激动剂，ED₅₀为0.02±0.01 mg/kg。

参考文献

1.Bugajski J, et al. The involvement of central alpha-adrenergic and histamine H2-receptors in the hypothermia induced by clonidine in the rat. Neuropharmacology. 1980 Jan;19(1):9-15.

2.Zhang YM, et al. Clonidine induces calcitonin gene-related peptide expression via nitric oxide pathway in endothelial cells. Peptides. 2009 Sep;30(9):1746-52.

3.Jentsch JD, et al. Clonidine and guanfacine attenuate phencyclidine-induced dopamine overflow in rat prefrontal cortex: mediating influence of the alpha-2A adrenoceptor subtype. Brain Res. 2008 Dec 30;1246:41-6.

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