Echinacoside松果菊苷(海胆苷/紫锥菊苷) Wnt/β-catenin通路抑制剂|CAS 82854-37-3（53052ES）

Echinacoside，又称松果菊苷、海胆苷或紫锥菊苷，是从Cistanche salsa中分离得到的一种苯乙醇类天然多酚化合物，有抗衰老、提高免疫力、抗氧化和神经保护的药理效果。Echinacoside可以抑制Wnt/β-catenin信号通路，还可以活化Trk受体及其下游信号通路。

参考文献

[1]. Tang C, et al. Echinacoside inhibits breast cancer cells by suppressing the Wnt/β-catenin signaling pathway. Biochem Biophys Res Commun. 2020 May 21;526(1):170-175.

[2]. Zhu M, et al. Transient exposure to echinacoside is sufficient to activate Trk signaling and protect neuronal cells from rotenone. J Neurochem. 2013 Feb;124(4):571-80.

[3]. Li F, et al. Echinacoside promotes bone regeneration by increasing OPG/RANKL ratio in MC3T3-E1 cells. Fitoterapia. 2012 Dec;83(8):1443-50.

[4]. Li F, et al. Antiosteoporotic activity of echinacoside in ovariectomized rats. Phytomedicine. 2013 Apr 15;20(6):549-57.

[5]. Li X, et al. Echinacoside ameliorates D-galactosamine plus lipopolysaccharide-induced acute liver injury in mice via inhibition of apoptosis and inflammation. Scand J Gastroenterol. 2014 Aug;49(8):993-1000.

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