Ridaforolimus (Deforolimus, MK-8669, AP23573)是一种新的雷帕霉素类似物，也是一种新型高效的选择性mTOR抑制剂，在HT-1080细胞中其IC₅₀为0.2 nM。

参考文献

[1] Rivera, V. M., et al. (2011) Ridaforolimus (AP23573; MK-8669), a potent mTOR inhibitor, has broad antitumor activity and can be optimally administered using intermittent dosing regimens. Mol Cancer Ther. 10, 1059-1071.

[2] Hernandez, S. F., et al. (2016) Ridaforolimus improves the anti-tumor activity of dual HER2 blockade in uterine serous carcinoma in vivo models with HER2 gene amplification and PIK3CA mutation. Gynecol Oncol. 141, 570-579.

冰袋运输。粉末直接保存于-20℃，有效期3年。建议分装后-20℃干燥保存，避免反复冻融。