AR-A014418 (AR A014418, AR 0133418, AR0133418, GSK 3β inhibitor VIII, AR 014418, AR014418, AR-014418) 是一种有效、细胞渗透性、ATP竞争性的GSK3β抑制剂（IC50和Ki值分别为104 nM和38 nM）。小鼠实验中显示出AR-A014418可缓解疼痛的作用，此外还发现可以抑制胰腺癌细的增殖。 

参考文献

[1]. Kunnimalaiyaan S, et al. Glycogen synthase kinase-3 inhibitor AR-A014418 suppresses pancreatic cancer cell growth via inhibition of GSK-3-mediated Notch1 expression. HPB (Oxford). 2015 Sep;17(9):770-6.

[2]. Gould TD, et al. AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test. Int J Neuropsychopharmacol. 2004 Dec;7(4):387-90.

冰袋运输。粉末直接保存于-20℃，有效期2年。溶于DMSO。建议分装后-20℃避光保存，避免反复冻融。