Pyrvinium pamoate（Pyrvinium embonate、扑蛲灵、吡维铵、吡维氯铵、恩波酸吡维铵、恩波吡维铵）是一种可治疗肠道蠕虫病的驱虫药物，一种古老的治疗蛲虫病的驱虫药物，是Wnt有效抑制剂，被用于抑制Wnt /β-catenin信号通路的肿瘤研究。 

参考文献

[1] Sun Y, et al. In vitro and in vivo Study of Antifungal Effect of Pyrvinium Pamoate Alone and in Combination With Azoles Against Exophiala dermatitidis. Front Cell Infect Microbiol. 2020 Oct 23; 10:576975. doi: 10.3389/fcimb.2020.576975. PMID: 33194816; PMCID: PMC7649562.

[2] Feng J, et al. Blocking STAT3 by pyrvinium pamoate causes metabolic lethality in KRAS-mutant lung cancer. Biochem Pharmacol. 2020 Jul; 177:113960. doi: 10.1016/j.bcp.2020.113960. Epub 2020 Apr 13. PMID: 32298693.

[3] Sun Y, et al. Synergistic Effect of Pyrvinium Pamoate and Azoles Against Aspergillus fumigatus in vitro and in vivo. Front Microbiol. 2020 Nov 3; 11:579362. doi: 10.3389/fmicb.2020.579362. PMID: 33224118; PMCID: PMC7669749.

[4] Guan Q, et al. Identification of pyrvinium pamoate as an anti-tuberculosis agent in vitro and in vivo by SOSA approach amongst known drugs. Emerg Microbes Infect. 2020 Feb 4;9(1):302-312. doi: 10.1080/22221751.2020.1720527. PMID: 32013776; PMCID: PMC7034053.

[5] Xu F, et al. Anthelmintic pyrvinium pamoate blocks Wnt/β-catenin and induces apoptosis in multiple myeloma cells. Oncol Lett. 2018 Apr;15(4):5871-5878. doi: 10.3892/ol.2018.8006. Epub 2018 Feb 9. Erratum in: Oncol Lett. 2020 Nov;20(5):243. PMID: 29552217; PMCID: PMC5840576.

冰袋运输。粉末直接保存于-20℃，有效期2年。建议分装后-20℃干燥保存，避免反复冻融。