Flumazenil (Ro 15-1788)，又称氟马西尼、氟马尼、氟马泽尼或苯二氮革咪唑，是一种有竞争性的GABAA receptor拮抗剂，具有抗惊厥和抗癫痫作用，用于苯二氮类药物过量导致的镇静作用及定向障碍。氟马西尼与中枢苯二氮卓受体相互作用，拮抗苯二氮杂卓激动剂和反向激动剂的行为、神经和电生理效应。

参考文献

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2.Belzung C, et al. Flumazenil induces benzodiazepine partial agonist-like effects in BALB/c but not C57BL/6 mice. Psychopharmacology (Berl). 2000 Jan;148(1):24-32.

3.Fernandez-Guasti A, et al. Flumazenil blocks the anxiolytic action of allopregnanolone. Eur J Pharmacol. 1995 Jul 25;281(1):113-5.

4.Loscher W, et al. Effects of the non-NMDA antagonists NBQX and the 2,3-benzodiazepine GYKI 52466 on different seizure types in mice: comparison with diazepam and interactions with flumazenil. Br J Pharmacol. 1994 Dec;113(4):1349-57.

5.Moy SS, et al. Flumazenil blockade of anxiety following ethanol withdrawal in rats. Psychopharmacology (Berl). 1997 Jun;131(4):354-60.

冰袋运输。粉末直接保存于-20℃，有效期3年。建议分装后-20℃干燥保存，避免反复冻融。