Compound E (γ-Secretase-IN-1, DuPont E, γ-Secretase Inhibitor XXI)是具有细胞通透性强效的γ-secretase抑制剂，IC₅₀值为0.3 nM，抑制β-ammyloid的产生，具有潜在的抗阿尔茨海默病作用。

参考文献

1.Beher D, et al. Pharmacological knock-down of the presenilin 1 heterodimer by a novel gamma -secretase inhibitor: implications for presenilin biology. J Biol Chem. 2001 Nov 30;276(48):45394-402.

2.Rasul S, et al. Inhibition of gamma-secretase induces G2/M arrest and triggers apoptosis in breast cancer cells. Br J Cancer. 2009 Jun 16;100(12):1879-88.

冰袋运输。粉末直接保存于-20℃，有效期3年。建议分装后-20℃干燥保存，避免反复冻融。