Psoralidin（补骨脂定，补骨酯定）是一种从香豆素中提取出的天然产物，也是COX-2和5-LOX的双重抑制剂。Psoralidin不仅可以诱导ROS的生成，还能下调NOTCH信号通路，在转录上抑制Akt磷酸化和磷脂酰肌醇3激酶的激活。Psoralidin具有多种生物活性，如抗癌、抗炎、抗氧化、抗抑郁、胰岛素信号的调节等。Psoralidin还是雌激素受体(ER)α和ERβ的激动剂，IC50值分别为1.03 μM和24.6 μM。

参考文献

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[3] Li J, et al. Psoralidin inhibits the proliferation of human liver cancer cells by triggering cell cycle arrest, apoptosis and autophagy and inhibits tumor growth in vivo. J BUON. 2019 Sep-Oct;24(5):1950-1955. PMID: 31786860.

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冰袋运输。粉末直接保存于-20℃，有效期2年。建议分装后-20℃避光保存，避免反复冻融。