[ 1 ]SYMBIOSIS: synthetic manipulable biobricks via orthogonal serine integrase systems

[ 2 ]Anionic nanoplastic exposure induces endothelial leakiness

[ 3 ]Balancing Microthrombosis and Inflammation via Injectable Protein Hydrogel for Inflammatory Bowel Disease

[ 4 ]Bacillus-functionalized sewage sludge biochar boosts cabbage growth through improved nitrogen assimilation

[ 5 ]Nuclear Fructose-1,6-Bisphosphate Inhibits Tumor Growth and Sensitizes Chemotherapy by Targeting HMGB1

[ 6 ]Liposomal simvastatin potentiates intranasal H1N1 influenza subunit vaccine via increasing transcytosis of antigen and submucosal dendritic cell recruitment

[ 7 ]METTL16-mediated m6A modification of MSMO1 modulates cholesterol metabolism and activates MAPK-p38/NF-κB signaling in colorectal cancer

[ 8 ]Silencing of PpNRAMP5 improves manganese toxicity tolerance in peach (Prunus persica) seedlings

[ 9 ]HSV-1 infection-induced herpetic neuralgia involves a CCL5/CCR5-mediated inflammation mechanism

[ 10 ]Layer-by-layer silk fibroin microparticles for codelivery for treating refractory colonic lesions

[ 11 ]Gut microbiota-derived trimethylamine N-oxide contributes to cardiomyocyte pyroptosis and cardiac injury via the tRF-Glu–ANT1–GSDMD axis

[ 12 ]MRPL3 enhances mitochondrial function via the TOMM40/PGC-1α/TFAM axis to drive early recurrence in hepatocellular carcinoma

[ 13 ]SLC27A5 deficiency-induced reduction in long-chain fatty acid uptake is a pro-tumorigenic metabolic adaptation and confers sensitivity to glutaminase inhibition in hepatocellular carcinoma

[ 14 ]USP20, a Super-enhancer Regulated Gene, Promotes Acute Myeloid Leukemia Progression through CTNNB1 Deubiquitination

[ 15 ]Neuronal tetraspanin TSP-6 suppresses intestinal innate immunity by modulating dense-core vesicle release in Caenorhabditis elegans

[ 16 ]Eubacterium rectale Improves the Efficacy of Anti-PD1 Immunotherapy in Melanoma via l-Serine-Mediated NK Cell Activation

[ 17 ]Polychlorinated biphenyl quinone induces immunotoxicity via lymphocytes apoptosis and Th1-Th2 cell imbalance in C57BL/6 mice

[ 18 ]Fecal transplantation from young zebrafish donors efficiently ameliorates the lipid metabolism disorder of aged recipients exposed to perfluorobutanesulfonate

[ 19 ]Testicular toxicity of bisphenol compounds: Homeostasis disruption of cholesterol/testosterone via PPARα activation

[ 20 ]Bigel microspheres encapsulating supramolecular bioactives enabled by electrospraying for colon-targeted delivery and ulcerative colitis therapy

[ 21 ]Cytoplasmic and mitochondrial citrate synthases mediate cadmium detoxification and tolerance in plants

[ 22 ]4,5-Dichloro-2-n-octyl-4-isothiazolin-3-one induces obesogenic effects by targeting fatty acid synthase

[ 23 ]Structural characterization of a novel glucan from rice bran, evaluation of its potential antioxidant and anti-allergy activities

[ 24 ]Bioaccumulation and toxicity of perfluorooctanoic acid and perfluorooctane sulfonate in marine algae Chlorella sp.

[ 25 ]HULC targets the IGF1R–PI3K-AKT axis in trans to promote breast cancer metastasis and cisplatin resistance

[ 26 ]GSK872 and necrostatin-1 protect retinal ganglion cells against necroptosis through inhibition of RIP1/RIP3/MLKL pathway in glutamate-induced retinal excitotoxic model of glaucoma

[ 27 ]MK2 promotes Tfcp2l1 degradation via β-TrCP ubiquitin ligase to regulate mouse embryonic stem cell self-renewal

[ 28 ]Efficient gene editing through an intronic selection marker in cells

[ 29 ]Complete protection from Henosepilachna vigintioctopunctata by expressing long double-stranded RNAs in potato plastids

[ 30 ]KDM6A alternative splicing induced by 25(OH)D inhibits breast cancer cell stemness through repressing TRAP1 transcription

[ 31 ]Novel biofortification candidate: MTP1 increases microelement contents and decreases toxic heavy metal accumulation in grains

[ 32 ]Lnc90386 Sponges miR-33-5p to Mediate Mycoplasma gallisepticum-Induced Inflammation and Apoptosis in Chickens via the JNK Pathway

[ 33 ]Identification and Validation of Ferroptosis-Related LncRNA Signatures as a Novel Prognostic Model for Colon Cancer

[ 34 ]EZH2 Inhibitors Suppress Colorectal Cancer by Regulating Macrophage Polarization in the Tumor Microenvironment

[ 35 ]Circular RNA hsa_circ_0083756 promotes intervertebral disc degeneration by sponging miR-558 and regulating TREM1 expression

[ 36 ]Splicing factor arginine/serine-rich 8 promotes multiple myeloma malignancy and bone lesion through alternative splicing of CACYBP and exosome-based cellular communication

[ 37 ]Engineering a gut synthetic microbial community to enhance protein bioconversion from organic wastes by black soldier fly larvae

[ 38 ]Panaxatriol saponin ameliorates myocardial infarction-induced cardiac fibrosis by targeting Keap1/Nrf2 to regulate oxidative stress and inhibit cardiac-fibroblast activation and proliferation

[ 39 ]Deacetylation of ZKSCAN3 by SIRT1 induces autophagy and protects SN4741 cells against MPP+-induced oxidative stress

[ 40 ]Identification and trial application of qPL.C02 controlling petiole length demonstrated that short-petiole can potentially enhance high-density rapeseed yields

[ 41 ]Benzophenone-1 induced aberrant proliferation and metastasis of ovarian cancer cells via activated ERα and Wnt/β-catenin signaling pathways

[ 42 ]WUSCHEL-related homeobox genes cooperate with cytokinin to promote bulbil formation in Lilium lancifolium

[ 43 ]CircZXDC Promotes Vascular Smooth Muscle Cell Transdifferentiation via Regulating miRNA-125a-3p/ABCC6 in Moyamoya Disease

[ 44 ]Lactate Activates Germline and Cleavage Embryo Genes in Mouse Embryonic Stem Cells

[ 45 ]Systematic Annotation Reveals CEP Function in Tomato Root Development and Abiotic Stress Response

[ 46 ]TOR3A represses type I interferon production and limits viral clearance during respiratory syncytial virus infection

[ 47 ]Stilbene B10 induces apoptosis and tumor suppression in lymphoid Raji cells by BTK-mediated regulation of the KRAS/HDAC1/EP300/PEBP1 axis

[ 48 ]Ligustrazine alleviates psoriasis-like inflammation through inhibiting TRAF6/c-JUN/NFκB signaling pathway in keratinocyte

[ 49 ]Transcription factors GmERF1 and GmWRKY6 synergistically regulate low phosphorus tolerance in soybean

[ 50 ]Pterostilbene Confers Protection against Diquat-Induced Intestinal Damage with Potential Regulation of Redox Status and Ferroptosis in Broiler Chickens

[ 51 ]PIM3-AMPK-HDAC4/5 axis restricts MuERVL-marked 2-cell-like state in embryonic stem cells

[ 52 ]Neurobehavioral toxicity of paroxetine in Gambusia affinis: Dissociated behavioral syndromes and impaired monoaminergic neurotransmission

[ 53 ]N-methyl-N-nitrosourea induces zebrafish anomalous angiogenesis through Wnt/β-catenin pathway

[ 54 ]Transcriptome analysis reveals gene expression changes of the basidiomycetous yeast Apiotrichum mycotoxinivorans in response to ochratoxin A exposure

[ 55 ]Myoglobin promotes macrophage polarization to M1 type and pyroptosis via the RIG-I/Caspase1/GSDMD signaling pathway in CS-AKI

[ 56 ]Evaluation of 3,4,4,9-trichlorocarbanilide to zebrafish developmental toxicity based on transcriptomics analysis

[ 57 ]HSP70/TLR2 Orchestrates Melanocyte Ferroptosis in the Onset of Vitiligo

[ 58 ]Nuciferine Effectively Protects Mice against Acetaminophen-Induced Liver Injury

[ 59 ]Sirtuin 5‐mediated desuccinylation of PRDX6 inhibits ferroptosis and alleviates sepsis-associated acute kidney injury

[ 60 ]NtZFP66L1 Regulates Cold Tolerance in Tobacco by Modulating the ABA Signaling Pathway and the GLK1-Mediated Adaptive Pathway

[ 61 ]CdJACG1 integrates jasmonic acid signaling and CBF pathways to confer cold tolerance in bermudagrass (Cynodon dactylon)

[ 62 ]METTL3-mediated m6A on nascent RNA coordinates translational and transcriptional programs to activate the NLRP3 inflammasome in macrophages

[ 63 ]LncRNA OIP5-AS1 inhibits the lipopolysaccharide-induced inflammatory response and promotes osteogenic differentiation of human periodontal ligament cells by sponging miR-92a-3p

[ 64 ]Ethylene thiourea exposure induces neurobehavioral toxicity in zebrafish by disrupting axon growth and neuromuscular junctions

[ 65 ]11.4 T ultra-high static magnetic field has no effect on morphology but induces upregulation of TNF signaling pathway based on transcriptome analysis in zebrafish embryos

[ 66 ]Mulberry polyphenols (ABRU) promote bone formation and alleviate bone loss via dual regulation of bone metabolism

[ 67 ]Hepatocellular BChE as a therapeutic target to ameliorate hypercholesterolemia through PRMT5 selective degradation to restore LDL receptor transcription

[ 68 ]Mitochondrial-targeted cerium dioxide nanozymes enable the efficient regulation of oxidative stress and inflammation in acute lung injury

[ 69 ]Metabolomic and Transcriptomic Analyses Reveal the Differential Response Model of Cultivated Tea and Wild Tea Resources against Pestalotiopsis theae

[ 70 ]Anemoside B4 prevents chronic obstructive pulmonary disease through alleviating cigarette smoke-induced inflammatory response and airway epithelial hyperplasia

[ 71 ]Single-cell RNA sequencing reveals intra-tumoral heterogeneity of glioblastoma and a pro-tumor subset of tumor-associated macrophages characterized by EZH2 overexpression

[ 72 ]Cyclocarya paliurus Reprograms the Flavonoid Biosynthesis Pathway Against Colletotrichum fructicola.

[ 73 ]Survival over growth: Accelerated bursa of Fabricius development enhances immune resilience in heavy metal-exposed tree sparrows

[ 74 ]Identification and Validation of the lncRNA MYOSLID as a Regulating Factor of Necroptosis and Immune Cell Infiltration in Colorectal Cancer following Necroptosis-Related LncRNA Model Establishment

[ 75 ]Integrative Analysis of N6-Methyladenosine-Related Enhancer RNAs Identifies Distinct Prognosis and Tumor Immune Micro-Environment Patterns in Head and Neck Squamous Cell Carcinoma

[ 76 ]Rambutan genome revealed gene networks for spine formation and aril development

[ 77 ]Oxytocin ameliorates cardiac hypertrophy by inhibiting mitochondrial dysfunction and pyroptosis via AMPK/PGC-1α /TFAM pathway

[ 78 ]PcWRKY11, an II-d WRKY Transcription Factor from Polygonum cuspidatum, Enhances Salt Tolerance in Transgenic Arabidopsis thaliana

[ 79 ]Genome-Wide Expression Profiling Analysis of Kiwifruit GolS and RFS Genes and Identification of AcRFS4 Function in Raffinose Accumulation

[ 80 ]ZmLBD42 coordinates cell proliferation and organogenesis to enhance somatic embryogenesis and regeneration in maize

[ 81 ]dlo-miR827 Negatively Regulates Sucrose Accumulation by Targeting DlSPS1 in Longan (Dimocarpus longan Lour.) Fruit

[ 82 ]Apigenin mitigates cigarette smoke-elicited lung impairment via the orchestration of the PPARγ/PGC1α-FATP2 pathway and the amelioration of the gut microenvironment

[ 83 ]Microglial IL-1RA ameliorates brain injury after ischemic stroke by inhibiting astrocytic CXCL1-mediated neutrophil recruitment and microvessel occlusion

[ 84 ]Targeting RIG-I alleviates renal tubular epithelial cells PANoptosis during post-traumatic rhabdomyolysis

[ 85 ]Peptidylarginine deiminase 4-mediated neutrophil extracellular trap formation aggravates β-cell damage in type 1 diabetes: A multi-model study

[ 86 ]Mechanisms of Senescence-Related NKG2D Ligands Release and Immune Escape Induced by Chemotherapy in Neuroblastoma Cells

[ 87 ]An algal lectin griffithsin inhibits Hantaan virus infection in vitro and in vivo

[ 88 ]Transcranial focused ultrasound stimulation reduces vasogenic edema after middle cerebral artery occlusion in mice

[ 89 ]MicroRNA-126-3p/-5p Overexpression Attenuates Blood-Brain Barrier Disruption in a Mouse Model of Middle Cerebral Artery Occlusion

[ 90 ]Long Noncoding RNA Lx8-SINE B2 Interacts with Eno1 to Regulate Self-Renewal and Metabolism of Embryonic Stem Cells

[ 91 ]Identification of Three Viruses Infecting Mulberry Varieties

[ 92 ]A SGLT2 Inhibitor Dapagliflozin Alleviates Diabetic Cardiomyopathy by Suppressing High Glucose-Induced Oxidative Stress in vivo and in vitro

[ 93 ]Peptide FK2 attenuates inflammation and pro-fibrotic cellular transitions via targeting the IKKβ/NF-κB/TGF-β1 axis in renal fibrosis.

[ 94 ]EBF3 suppresses lung adenocarcinoma progression and immune evasion via transcriptional repression of CCL24

[ 95 ]Protective efficacy of Schizandrin B on ameliorating nephrolithiasis via regulating GSK3β/Nrf2 signaling-mediated ferroptosis in vivo and in vitro

[ 96 ]Dioscin modulates macrophages polarization and MDSCs differentiation to inhibit tumorigenesis of colitis-associated colorectal cancer

[ 97 ]Soybean transcription factors GmHSF-01 and GmNF-YC03 regulate the GmSRC7TN-mediated immune pathway

[ 98 ]IFN-Inducible SerpinA5 Triggers Antiviral Immunity by Regulating STAT1 Phosphorylation and Nuclear Translocation

[ 99 ]Hepatocellular Carcinoma Cell-Derived Exosomal miR-21-5p Induces Macrophage M2 Polarization by Targeting RhoB

[ 100 ]GhALKBH10 negatively regulates salt tolerance in cotton