Valganciclovir hydrochloride是一种口服抗病毒剂,能通过抑制腺病毒生长对免疫抑制仓鼠产生保护作用,可用于巨细胞病毒研究。
|
英文别名 (English Synonym) |
Valganciclovir HCl |
|
中文名称 (Chinese Name) |
缬更昔洛韦盐酸盐 |
|
靶点 (Target) |
CMV |
|
通路 (Pathway) |
Microbiology/Virology |
|
CAS号 (CAS NO.) |
175865-59-5 |
|
分子式 (Formula) |
C14H23ClN6O5 |
|
分子量 (Molecular Weight) |
390.82 |
|
纯度 (Purity) |
≥98% |
|
溶解性 (Solubility) |
溶于DMSO |
-25~-15℃保存，有效期3年
[1] Sugawara M, Huang W, Fei YJ, Leibach FH, Ganapathy V, Ganapathy ME. Transport of valganciclovir, a ganciclovir prodrug, via peptide transporters PEPT1 and PEPT2. J Pharm Sci. 2000 Jun,89(6):781-9. doi: 10.1002/(SICI)1520-6017(200006)89:6<781::AID-JPS10>3.0.CO,2-7. PMID: 10824137.[2]Toth K, Ying B, Tollefson AE, Spencer JF, Balakrishnan L, Sagartz JE, Buller RM, Wold WS. Valganciclovir inhibits human adenovirus replication and pathology in permissive immunosuppressed female and male Syrian hamsters. Viruses. 2015 Mar 23,7(3):1409-28. doi: 10.3390/v7031409. PMID: 25807051, PMCID: PMC4379578.
