盐酸罗贝胍是一种抗球虫药物，同时对耐甲氧西林金黄色葡萄球菌（MRSA）和耐万古霉素肠球菌（VRE）亦具有抑制活性。
|
英文别名 (English Synonym) |
Robenidine hydrochloride |
|
中文名称 (Chinese Name) |
盐酸氯苯胍 |
|
靶点 (Target) |
Anti-infection |
|
通路 (Pathway) |
Microbiology |
|
CAS号 (CAS NO.) |
25875-50-7 |
|
分子式 (Formula) |
C15H14Cl3N5 |
|
分子量 (Molecular Weight) |
370.66 |
|
纯度 (Purity) |
≥98% |
|
溶解性 (Solubility) |
溶于DMSO |
-25~-15℃保存，有效期3年
[1] Abraham RJ, Stevens AJ, Young KA, Russell C, Qvist A, Khazandi M, Wong HS, Abraham S, Ogunniyi AD, Page SW, O'Handley R, McCluskey A, Trott DJ. Robenidine Analogues as Gram-Positive Antibacterial Agents. J Med Chem. 2016 Mar 10;59(5):2126-38. doi: 10.1021/acs.jmedchem.5b01797. Epub 2016 Feb 10. PMID: 26765953. [2] Liu C, Wang SJ, Zhang Q, Shao YX. Influence of three coccidiostats on the pharmacokinetics of florfenicol in rabbits. Exp Anim. 2015;64(1):73-9. doi: 10.1538/expanim.14-0064. Epub 2014 Oct 16. PMID: 25319758; PMCID: PMC4329518.
