Ceftriaxone sodium hydrate是一种广谱头孢菌素抗生素,通过抑制GSK3β与Aurora B等靶点,发挥抗菌、抗炎、抗肿瘤及抗氧化作用,可用于治疗细菌感染与脑膜炎的研究。
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英文别名 (English Synonym) |
Ceftriaxone Sodium Trihydrate |
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中文名称 (Chinese Name) |
头孢曲松钠；头孢曲松钠水合物 |
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靶点 (Target) |
Anti-infection |
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通路 (Pathway) |
Microbiology/Virology |
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CAS号 (CAS NO.) |
104376-79-6 |
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分子式 (Formula) |
C18H16N8O7S3·7/2H2O·2Na |
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分子量 (Molecular Weight) |
663.61 |
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纯度 (Purity) |
≥98% |
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溶解性 (Solubility) |
溶于DMSO |
-25~-15℃保存，有效期3年
[1] Zhang Y, Zhang X, Qu S. Ceftriaxone Protects Astrocytes from MPP(+) via Suppression of NF-κB/JNK/c-Jun Signaling. Mol Neurobiol. 2015 Aug,52(1):78-92. doi: 10.1007/s12035-014-8845-z. Epub 2014 Aug 12. PMID: 25112679.[2]Hakimizadeh E, Hassanshahi J, Kaeidi A, Nematollahi MH, Taghipour Z, Rahmani M, Fatemi I. Ceftriaxone improves hepatorenal damages in mice subjected to D-galactose-induced aging. Life Sci. 2020 Oct 1,258:118119. doi: 10.1016/j.lfs.2020.118119. Epub 2020 Jul 17. PMID: 32682915.
