β-Arbutin）是一种常用的脱色剂,其作用源于对黑色素细胞中酪氨酸酶的竞争性抑制。该物质也是一种具有抗氧化、抗炎及抗肿瘤活性的天然多酚。
|
英文别名 (English Synonym) |
Arbutin |
|
中文名称 (Chinese Name) |
熊果苷 |
|
靶点 (Target) |
Tyrosinase |
|
通路 (Pathway) |
Natural Products |
|
CAS号 (CAS NO.) |
497-76-7 |
|
分子式 (Formula) |
C12H16O7 |
|
分子量 (Molecular Weight) |
272.25 |
|
纯度 (Purity) |
≥98% |
|
溶解性 (Solubility) |
溶于水（≥50 mg/mL），溶于DMSO，溶于甲醇 |
|
结构式（Structure） |
 |
-25~-15℃保存，有效期3年。
[1] Jiang L, Wang D, Zhang Y, Li J, Wu Z, Wang Z, Wang D. Investigation of the pro-apoptotic effects of arbutin and its acetylated derivative on murine melanoma cells. Int J Mol Med. 2018 Feb,41(2):1048-1054. doi: 10.3892/ijmm.2017.3256. Epub 2017 Nov 16. PMID: 29207077.[1] Nalban N, Sangaraju R, Alavala S, Mir SM, Jerald MK, Sistla R. Arbutin Attenuates Isoproterenol-Induced Cardiac Hypertrophy by Inhibiting TLR-4/NF-κB Pathway in Mice. Cardiovasc Toxicol. 2020 Jun,20(3):235-248. doi: 10.1007/s12012-019-09548-3. PMID: 31485892.
