双模式mRNA建库试剂盒(兼容Illumina和MGI) Hieff NGS® Ultima Dual-mode mRNA Library Prep Kit（12309ES）

[ 1 ]The 1000 Chinese Pangenome empowers medical and population genetics

[ 2 ]Senotoxins target senescence via lipid binding specificity, ion imbalance and lipidome remodeling

[ 3 ]Extracellular Vesicles From Human Fallopian Tubes Enhance IVF Embryo Development and Contain Functional Proteins Including YWHAZ

[ 4 ]CXCR5+ monocyte emigration impairs the radiation-induced antitumor immune response

[ 5 ]A scalable two-step genome editing strategy for generating full-length gene-humanized mice at diverse genomic loci

[ 6 ]An engineered linear cap-independent mRNA vaccine with intrinsic adjuvanticity induces potent anti-tumor immunity in mice

[ 7 ]Sex-specific cardioprotective role of miR-30a-5p through estrogen-dependent mechanisms in a mouse model of heart failure

[ 8 ]Ginseng-derived vesicle-like nanoparticles deliver pgi-MIR6136a-p3 for sepsis therapy via ELF3/NF-κB signaling axis

[ 9 ]Universal off-the-shelf TGF-β1-knockout whole-tumor cell vaccine overcomes immunotherapy resistance in pMMR/MSS tumors

[ 10 ]Gut Lactate Boosts Ruminococcus via Histone Lactylation to Mediate Time-Restricted Feeding Protection in Crohn's Disease

[ 11 ]Single‐Cell Transcriptomic Analysis of Tumor Heterogeneity and the Microenvironment in Pseudomyxoma Peritonei

[ 12 ]α-Synuclein aggregation and brain atrophy in SNCA-A53T transgenic monkeys correlate with parkinsonism

[ 13 ]Mitofusin-2 suppresses tumor immune escape through EGFR/STAT3-mediated PD-L1 transcription

[ 14 ]CD44/POU2F2/BCL9L axis mediates MIF-driven SPP1+TAM activation in colorectal cancer metastasis

[ 15 ]Akkermansia muciniphila-derived 5-MIAA blunts colitis-associated tumorigenesis by modulating colonic SLC26A3/pSTAT3 signaling

[ 16 ]Bilobalide attenuates Salmonella typhimurium virulence by repressing the quorum sensing and Type III secretion system effectors

[ 17 ]Absorption, accumulation, physiological responses, and mechanistic insights into tomato (Solanum lycopersicum L.) to polystyrene microplastics

[ 18 ]Subacute dimethylated monothioarsenate (DMMTA) exposure induces hepatotoxicity and disrupts the gut microbiota-bile acid-liver axis: a multi-omics study in mice

[ 19 ]Synthetic microbial community shields wheat from cadmium: Coordinating host metabolic reprogramming and rhizosphere microenvironment regulation

[ 20 ]Stage-resolved multi-omics links flavonoid accumulation to antioxidant capacity in Isatis indigotica fruit

[ 21 ]Elucidating the Mechanisms Underlying Differential Anthocyanin Biosynthesis and Its Link to Stem Color and Root Isoflavonoid Levels in Astragalus membranaceus var. mongholicus

[ 22 ]Sugar stress attenuates fruity aroma in sweet wine by suppressing ethyl ester biosynthesis: Insights from integrated sensory, metabolome, and transcriptomic analyses

[ 23 ]Multi-omics analysis reveals the aging mechanism during Baobaoqu storage for the production of Wuliangye Baijiu

[ 24 ]Tumor cell-intrinsic PD-1 in malignant ascites drives ovarian cancer progression via MAPK/ERK signaling

[ 25 ]Heat shock protein modulates cell expansion via ROS homeostasis

[ 26 ]Alternative splicing of PeGA20ox1 impairs PeRAP2-1-mediated GA/ABA homeostasis leading to short internodes in the dwarf variant of Moso bamboo, Phyllostachys edulis ‘Heterocycla’

[ 27 ]Comprehensive genome-wide identification, molecular characterisation, and expression profiling of HSP gene families in Bufo gargarizans

[ 28 ]Developmental Toxicity of Chlorinated Polyfluorinated Ether Sulfonate (F-53B), a Perfluorooctane Sulfonate (PFOS) Alternative, in Embryos and Larvae of Blotched Snakehead (Channa maculata)

[ 29 ]Benzophenone-2 Disrupts Craniofacial Cartilage Development via esr2a-Dependent Inhibition of Endothelin Signaling in Zebrafish Larvae

[ 30 ]Ecotoxicological insights into UV-P-induced immunotoxicity and bacterial infection risk in marine medaka (Oryzias melastigma)

[ 31 ]Dual roles of pea CCD7 in strigolactone-dependent and -independent processes as revealed by transcriptomic profiling and mycorrhization assays

[ 32 ]Genetic dissection of cadmium accumulation in tea plants under nonphytotoxic field conditions

[ 33 ]Integrated ATAC-seq and mRNA-seq analyses on granulosa cells identify key regulators of follicle selection in chickens

[ 34 ]Intermittent oxygenation during peak fermentation: Effect on fermentation kinetics, volatile composition, and sensory properties

[ 35 ]Zeb2 Controls Retinal Physiological and Pathological Angiogenesis by Regulating Astrocyte Proliferation and Differentiation

[ 36 ]The NADPH oxidase inhibitor Vas2870 prevents myocyte ferroptosis and improves cardiac remodelling and function in doxorubicin-induced cardiomyopathy

[ 37 ]Pulsed light treatment delays softening of harvested ‘Mopan’ persimmon by modulating ethylene biosynthesis and signaling pathways

[ 38 ]2-Nonanone suppresses postharvest gray mold by disrupting ROS homeostasis and pathogenicity of Botrytis cinerea

[ 39 ]Chromosome-level genome assembly of the teak defoliator Hyblaea puera Cramer (Lepidoptera: Hyblaeidae)

[ 40 ]Chromosome-level genome assembly of the alpine extremophyte Tibetan snow lotus, Saussurea hypsipeta Diels

[ 41 ]p-CA treatment influences the accumulation of anthocyanin and flavonoids and enhances the fruit quality and storage characteristics of blood orange during storage

[ 42 ]A Programmable Eukaryotic Argonaute Nuclease with Dual DNA and RNA Cleavage Activity from Thermophilic Fungus Thermochaetoides thermophila

[ 43 ]Dysregulation of the microbiota-gut-brain axis induced by chronic pancreatitis mediates anxiety- and depression-like behaviors in mice

[ 44 ]Post-Heading High Nighttime Temperature Impairs Grain Protein-Starch Balance and Rice Quality Through Altering Nitrogen Metabolism

[ 45 ]Polystyrene nanoplastics modulate neurite length in a size-specific manner

[ 46 ]A Synthetic Community from Campeiostachys nutans Rhizosphere in the Qinghai-Tibet Plateau Endow Alfalfa with the Ability to Resist Drought and Cold

[ 47 ]Nrf2 Drives Deltamethrin Resistance of Spodoptera frugiperda by Directly Upregulating Multiple Detoxification Enzyme Genes

[ 48 ]A chromosome-scale genome assembly of Quercus gilva: Insights into the evolution of Quercus section Cyclobalanopsis (Fagaceae).

[ 49 ]Aerobic Exercise Promotes Hippocampal Neurogenesis and Ameliorates Cognitive Dysfunction Induced by Unilateral Labyrinthectomy

[ 50 ]tRF-Gly-CCC-012 enhances malignant process in pancreatic cancer via the HNRNPC/PHGDH axis

[ 51 ]Transcriptional redirection of quercetin-oriented flavonoid biosynthesis underpins ecotype differentiation in Tetrastigma hemsleyanum

[ 52 ]Integrative epigenomic and transcriptomic profiling reveals organ-specific and coordinated cold stress responses in the brain and gill of Nile tilapia

[ 53 ]Multi-omics reveals that specific responses to drought stress in cotton roots of various genotypes are mediated by diverse multi-pathway collaboration of phenylpropanoid pathway

[ 54 ]Corn silk extract ameliorates cisplatin-induced cardiac injury by restoring mitochondrial function and suppressing ferroptosis

[ 55 ]Integrative Metabolomic and Transcriptomic Profiling Reveals the Chemical and Molecular Basis for Aroma Divergence in Isatis Fruits

[ 56 ]Multi-omics-guided discovery: yeast protein alleviates glucocorticoid-induced muscle atrophy through dual activation of IGF-1/PI3K/Akt/FOXO and CaMKK/AMPK signaling pathways

[ 57 ]Molecular and Metabolic Regulation of Anthocyanin Accumulation under Phosphorus Stress in Purple-Fleshed Sweet Potato

[ 58 ]Transcriptional regulation of amygdalin biosynthesis and catabolism during kernel development in Prunus mandshurica

[ 59 ]Integrated transcriptomic and metabolomic profiling unravels the altitude-induced regulatory mechanism of quality-related metabolites in tea plants

[ 60 ]Hypoglycemic effects of Gegen Qinlian decoction and its food-medicine homologous alternative formula against type 2 diabetes

[ 61 ]CD80-Mediated T-Cell Suppression by Cancer Stem-like Cells in Head and Neck Squamous Cell Carcinoma

[ 62 ]Comparative transcriptome and physiological analyses unveil differential responses of Panax ginseng adventitious roots to iron vs. zinc deficiency

[ 63 ]miR-318 regulates juvenile hormone biosynthesis to control ovarian development in Bactrocera dorsalis

[ 64 ]Ferrous sulfate induces ferroptosis-like cell death in Trichosporon asahii

[ 65 ]The ethyl acetate extract from Trichoderma viride fermentation acts by downregulating the leukocyte transendothelial migration signaling pathway to induce ferroptosis in triple-negative breast cancer cells

[ 66 ]Elaborating the molecular characteristics of corals’ different tolerance to environmental stress in Sanya Luhuitou based on multi-omics analysis

[ 67 ]SiYSL1 regulates the iron absorption, transportation, and grain accumulation in foxtail millet

[ 68 ]From a Multi-Omics Signature to a Therapeutic Candidate: Computational Prediction and Experimental Validation in Liver Fibrosis

[ 69 ]Single-cell transcriptomic mapping of patient-derived primary liver cancer organoids reveals molecular subtypes and guides precision drug targeting

[ 70 ]An efficient C-to-U RNA recorder as a tool for profiling targets of RNA-binding proteins

[ 71 ]Sexually Dimorphic and Intersex-Specific Transcriptional Responses in Cherax quadricarinatus Hepatopancreas Following Methyl Farnesoate Exposure

[ 72 ]Deciphering lipid biosynthesis and regulation in Isatis species through combined metabolomic and transcriptomic analysis

[ 73 ]Multi-Omics Integration Reveals Temporal Partitioning Between Metabolic Priming and Proliferative Expansion in PGPR-Treated Cherry Plants

[ 74 ]The identification of gibberellin 2-oxidase gene family in cotton and functional analysis

[ 75 ]A Distinct Defense Strategy: The Molecular Basis of WSSV Tolerance in Macrobrachium nipponense Revealed by Comparative Transcriptomics with Litopenaeus vannamei

[ 76 ]Ginsenoside Re Ameliorates UVB-Induced Skin Photodamage by Modulating the Glutathione Metabolism Pathway: Insights from Integrated Transcriptomic and Metabolomic Analyses

[ 77 ]Sequence Variations in MYB (v-myb Myeloblastosis Viral Oncogene Homolog) Genes Impair Anthocyanin Biosynthesis and Contribute to Yellow Flower Phenotype in Rehmannia glutinosa

[ 78 ]Genome-Wide Dissection of the TCP Gene Family in Peach and Expression Analysis Under Drought Stress

[ 79 ]Comprehensive Transcriptomic and Proteomic Profiling of CILD40 with Novel Compound Heterozygous Mutations of DNAH9

[ 80 ]Dachaihu decoction ameliorates septic intestinal injury via modulating the gut microbiota and glutathione metabolism as revealed by multi-omics

[ 81 ]Integrated physiological and transcriptomic analyses reveal that HmPIF1 overexpression confers lead stress tolerance in Hydrangea

[ 82 ]NMN/NAD+/SIRT1 axis activates NAMPT to ameliorate H2O2-triggered the impairment of progesterone synthesis in ovarian granulosa cells

[ 83 ]Alterations of meat quality, lipid composition and metabolite profiles in breast meat of Chinese indigenous chickens after the onset of egg production

[ 84 ]Role of Alternative Splicing and Polyadenylation in Regulation of Spleen Development

[ 85 ]Dysregulation of cholesterol metabolism decreases cervical cancer cells’ migratory ability caused by propofol in vitro

[ 86 ]Unraveling the mechanism of hepatocyte response to flusilazole: Insights from multi-omics analysis and molecular docking

[ 87 ]NR4A1 mediates chemotherapy‑induced senescence via the PI3K/AKT pathway in gastric cancer cells

[ 88 ]Transcriptomic analysis reveals the hepatic response mechanisms of the Chinese spiny frog (Quasipaa spinosa) to Citrobacter freundii infection

[ 89 ]Defense Responses of Cucumber and Cowpea to Frankliniella occidentalis Infestation Influence the Growth, Development, and Host Preferences of the Pest

[ 90 ]Enhanced Polar Auxin Transport and Reduced Brassinosteroid Activity Drive Internode Elongation in Chinese Fir (Cunninghamia lanceolata)

[ 91 ]Concentration-Dependent Regulation of Ginger Growth and Quality by Abscisic Acid: Insights from Integrated Metabolomic and Transcriptomic Analyses

[ 92 ]Pyroxsulam Boosts Wheat Tolerance to Bixlozone: Effects and Mechanisms

[ 93 ]Integrative Transcriptomics Reveals Regulatory Networks Underlying Fatty Acid and Lacquer Wax Formation in Fruit of Toxicodendron vernicifluum

[ 94 ]Integrative Hormone Metabolomic, Transcriptomic, and miRNA Sequencing Analyses Reveal Brassinosteroid-Mediated Sex Differentiation in Walnut Flower Buds

[ 95 ]Malic acid modulates adventitious root elongation through auxin accumulation and MdTCP17-mediated regulation in apple

[ 96 ]Lactobacillus Regulates the Specificity of Polysaccharides Derived From Pericarpium Citri Reticulatae “Chachiensis” to Alleviate High-Fat Diet–Induced Depression-Like Behavior

[ 97 ]miR-26a-5p inhibits the proliferation and myogenic differentiation of chicken BMSCs by targeting MDFIC

[ 98 ]Humanin and MOTS-c Attenuate Atrial Fibrillation by Suppressing Fibrosis and Mitochondrial Dysfunction

[ 99 ]Physiological, Biochemical and Transcriptomic Mechanisms Underlying the Mitigation of Salt Stress in Cabernet Sauvignon Grapevine Seedlings by Foliar Application of a Seaweed-Based Biostimulant (Jinmei Extract)

[ 100 ]Transcriptome Profiling of Powdery Mildew-Stressed ‘Yeniang No. 2’ Grapevine Reveals Differential Expression, Alternative Splicing, and the Identification of 1232 Annotated Novel Genes