Bepotastine besilate (TAU 284, TAU284),又称苯磺酸贝托司汀、苯磺酸贝他斯汀、苯磺酸贝托斯汀或苯磺酸贝他司汀,是可口服的组胺H1受体(histamine H1 receptor)选择性拮抗剂,抗真菌类药物,临床上用于治疗过敏性结膜炎。
参考文献
[1] Kida T, et al. Bepotastine besilate, a highly selective histamine H(1) receptor antagonist, suppresses vascular hyperpermeability and eosinophil recruitment in in vitro and in vivo experimental allergic conjunctivitis models. Exp Eye Res. 2010 Jul;91(1):8.
[2] Kamata Y, et al. Bepotastine besilate downregulates the expression of nerve elongation factors in normal human epidermal keratinocytes. J Dermatol Sci. 2018 Apr 23:S0923-1811(18)30186-5.
[3] Da Prada M, et al. Neurochemical profile of moclobemide, a short-acting and reversible inhibitor of monoamine oxidase type A. J Pharmacol Exp Ther. 1989 Jan;248(1):400-14.
冰袋运输。粉末直接保存于-25~-15℃,有效期3年。建议溶解分装后于-25~-15℃干燥保存,避免反复冻融。