VEGFR2 is a receptor for vascular endothelial growth factor (VEGF) that mediates virtually all known cellular responses to VEGF. VEGFR2 is mainly expressed in endothelial cells and is up-regulated in tumor vascular system. Inhibition of VEGFR2 activity and its downstream signal is an important target for the treatment of angiogenic diseases.
性能参数
Synonyms |
KDR;Flk-1 |
Uniprot No. |
P35968 |
Source |
Recombinant Human VEGFR2 Protein is expressed from HEK293 Cells with His tag at the C-terminal. It contains Ala 20-Glu 764. |
Molecular Weight |
The protein has a predicted MW of 85.22 kDa. And it migrates as 130 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Purity |
> 95% as determined by SDS-PAGE. |
Endotoxin |
<0.1 EU per 1μg of the protein by the LAL method. |
Formulation |
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). |
Reconstitution |
Centrifuge tubes before opening. Dissolve lyophilized protein with sterile PBS to ensure the concentration is greater than 100 ug/mL. |
储存条件
The product should be stored at -25~-15℃ for 1 year from date of receipt.
2-7 days, 2 ~8 °C under sterile conditions after reconstitution.
3 months, -25~-15℃ under sterile conditions after reconstitution.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
注意事项
1.Please operate with lab coats and disposable gloves,for your safety.
2.This product is for research use only.
产品数据
Ver. CN20230531