分子生物学
IVD分子诊断
细胞培养与分析
蛋白研究
重组蛋白
细胞因子
抗体
高通量测序建库
病原检测UCF系列
生物医药
工具酶
抑制剂激活剂与常用试剂
仪器
耗材
Recombinant Human VEGF 165 Protein, His Tag 重组人血管内皮生长因子-165
产品详情
FAQ
产品文档
已发表文献
产品介绍


Vascular endothelial growth factor (VEGF) is a highly specific mitogen for vascular endothelial cells. Five VEGF isoforms are generated as a result of alternative splicing from a single VEGF gene. These isoforms differ in their molecular mass and in biological properties such as their ability to bind to cell-surface heparan-sulfate proteoglycans. The 165-amino acid form of vascular endothelial growth factor (VEGF165) is a mitogen for vascular endothelial cells and a potent angiogenic factor. Human VEGF165 shares 88% aa sequence identity with corresponding regions of mouse and rat, 96% with porcine, 95% with canine, and 93% with feline, equine and bovine VEGF, respectively. Co-expression of NRP1 and (VEGFR-2) KDR on the surface of endothelial cells (EC) enhances VEGF165 binding to KDR and EC chemotaxis in response to VEGF165. Overexpression of NRP1 by prostate tumor cells in vivo results in increased tumor angiogenesis and growth.

产品性质
产品特色

高纯度、高活性、低内毒素、高批间一致性

应用案例

存储条件

-25 ~ -15℃保存,收到货之后有效期1年。
复溶后,无菌条件下,-85 ~ -65℃保存,3个月有效期。

COA
联系我们
购物车
客服
转染试用