The human asialoglycoprotein receptor (ASGPR) is an endocytic recycling receptor that belongs to the long-form subfamily of the C-type/Ca+2-dependent lectin family. ASGR1 is a liver-specific surface marker that is exclusively expressed in liver and mediates internalization and lysosomal degradation of blood asialoglycoproteins.
产品性质
Synonyms |
ASGP-R 1; ASGPR 1; Hepatic lectin 1; HL-1; mHL-1; Asgr1; Asgr-1; |
Uniprot No. |
|
Source |
Recombinant Human ASGR1 Protein is expressed from HEK293 Cells with His tag at the N-terminal. It contains Gln62-Leu291. |
Molecular Weight |
The protein has a predicted MW of 27.49 kDa. Due to glycosylation, the protein migrates to 38-55 kDa based on Tris-Bis PAGE result. |
Purity |
> 95% as determined by SDS-PAGE and HPLC |
Endotoxin |
< 1.0 EU per 1μg of the protein by the LAL method. |
Formulation |
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL` is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water. |
运输与保存方法
The products are shipped with ice pack and can be stored at -20℃ for 1 year.
2-7 days, 2 to 8 °C under sterile conditions after reconstitution.
3 months, -20 °C under sterile conditions after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please avoid freeze-thaw cycles.
注意事项
1.For your safety and health, please wear lab coats and disposable gloves for operation.
2.For research use only!
产品数据
HB221206