Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state.They are sialoadhesin/CD169/Siglec-1, CD22/Siglec-2, CD33/Siglec-3, Myelin-Associated Glycoprotein (MAG/Siglec-4a) and Siglecs 5 to 11. To date, no Siglec has been shown to recognized any cell surface ligand other than sialic acids, suggesting that interactions with glycans containing this carbohydrate are important in mediating the biological functions of Siglecs.

 

产品性质

Synonyms	CD33 molecule; CD33; FLJ00391; gp67; Siglec3; Siglec-3; p67
Uniprot No.	P20138-1
Source	Recombinant Biotinylated Human Siglec-3/CD33 Protein is expressed from HEK293 Cells with His tag and Avi tag at the C-terminal. It contains Asp18-His259.
Molecular Weight	The protein has a predicted MW of 29.6 kDa. Due to glycosylation, the protein migrates to 48-58 kDa based on Tris-Bis PAGE result.
Physical Appearance	Liquid Solution
Purity	> 95% as determined by SDS-PAGE and > 90% as determined by HPLC
Endotoxin	< 1.0 EU per 1μg of the protein by the LAL method.
Formulation	Supplied as 0.22μm filtered solution in 20mM PB, 500mM NaCl (pH 8.0).

 

运输与保存方法

The products are shipped with ice pack and can be stored at -80°C for 1 year.

Recommend to aliquot the protein into smaller quantities for optimal storage. Please do not repeated freeze-thaw cycles.

 

注意事项

1.For your safety and health, please wear lab coats and disposable gloves for operation.

2.For research use only!