Carbamazepine卡马西平
产品介绍
Carbamazepine (Carbatrol, CBZ, NSC 169864, NSC169864),又称卡马西平,三环亲脂性化合物,是一种钠离子通道抑制剂,一种抗惊厥药物,用于治疗癫痫发作。Carbamazepine通过减少多突触反应和阻断强直后期强化发挥抗惊厥活性。
产品性质
产品特色
参考文献
1.Willow M, et al. Inhibition of binding of [3H]batrachotoxinin A 20-alpha-benzoate to sodium channels by the anticonvulsant drugs diphenylhydantoin and carbamazepine. Mol Pharmacol. 1982 Nov;22(3):627-35.
2.Okada, M., et al., Biphasic effects of carbamazepine on the dopaminergic system in rat striatum and hippocampus. Epilepsy Res, 1997. 28(2): p. 143-53.
3.Serra M, et al. Steroidogenesis in rat brain induced by short- and long-term administration of carbamazepine. Neuropharmacology. 2000 Sep;39(12):2448-56.
存储条件
冰袋运输。粉末直接保存于-20℃,有效期3年。建议分装后-20℃干燥保存,避免反复冻融。
COA
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