Hydroxychloroquine sulfate硫酸羟氯喹 抗疟疾药/血红素聚合酶抑制剂|CAS 747-36-4（53628ES）

Hydroxychloroquine sulfate (HCQ sulfate, NSC 4375, NSC4375)，又称硫酸羟氯喹或硫酸羟基氯喹，是一种合成的抗疟疾药，也是血红素聚合酶抑制剂，具有抗炎、免疫调节活性，临床上用于治疗系统性红斑狼疮、类风湿关节炎等自身免疫病。

参考文献

1.Ramser B, et al. Hydroxychloroquine modulates metabolic activity and proliferation and induces autophagic cell death of human dermal fibroblasts. J Invest Dermatol. 2009 Oct;129(10):2419-26.

2.Lee HO, et al. Hydroxychloroquine Destabilizes Phospho-S6 in Human Renal Carcinoma Cells. PLoS One. 2015 Jul 2;10(7):e0131464.

3.Bourke L, et al. Hydroxychloroquine Protects against Cardiac Ischaemia/Reperfusion Injury In Vivo via Enhancement of ERK1/2 Phosphorylation. PLoS One. 2015 Dec 4;10(12):e0143771.

4.Yao X, et al. In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Clin Infect Dis. 2020 Jul 28;71(15):732-739.

冰袋运输。粉末直接保存于-20℃，有效期3年。建议分装后-20℃干燥保存，避免反复冻融。