IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune systems. The IL-17 family of cytokines includes six members, IL-17/IL-17A, IL-17B, IL-17C, IL-17D, IL-17E/IL-25, and IL-17F, which are produced by multiple cell types. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis, and multiple sclerosis.
高纯度、高活性、低内毒素、高批间一致性
-25 ~ -15℃保存,收到货之后有效期1年。 复溶后,无菌条件下,2~8℃保存,7天有效期。复溶后, 无菌条件下,-85 ~ -65℃保存,3个月有效期。
[90116ES]Recombinant Human IL-17B 重组人白介素-17B
[90117ES]Recombinant Human IL-17F 重组人白介素-17F
[90177ES]Recombinant Rat IL-17A 重组大鼠白介素-17A
[93796ES]Biotinylated Human IL-17A/CTLA-8 Protein, His-Avi Tag
[94118ES]Recombinant Human IL-25/IL-17E Protein,His Tag 重组人白介素-25
[93940ES]Recombinant Human IL-17R alpha/CD217 Protein,His Tag
[94017ES]Recombinant Mouse IL-17R alpha/CD217 Protein,hFc Tag