Amodiaquine是一种口服有效的4-氨基喹啉类抗疟药，它还能有效抑制组胺N-甲基转移酶，并作为Nurr1受体激动剂（EC50≈20μM）通过特异性结合其配体结合域发挥抗炎作用。
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-25~-15℃避光保存，有效期3年。
[1] Kim CH, Han BS, Moon J, Kim DJ, Shin J, Rajan S, Nguyen QT, Sohn M, Kim WG, Han M, Jeong I, Kim KS, Lee EH, Tu Y, Naffin-Olivos JL, Park CH, Ringe D, Yoon HS, Petsko GA, Kim KS. Nuclear receptor Nurr1 agonists enhance its dual functions and improve behavioral deficits in an animal model of Parkinson's disease. Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):8756-61. doi: 10.1073/pnas.1509742112. Epub 2015 Jun 29. PMID: 26124091; PMCID: PMC4507186.[2]Kinoshita K, Matsumoto K, Kurauchi Y, Hisatsune A, Seki T, Katsuki H. A Nurr1 agonist amodiaquine attenuates inflammatory events and neurological deficits in a mouse model of intracerebral hemorrhage. J Neuroimmunol. 2019 May 15;330:48-54. doi: 10.1016/j.jneuroim.2019.02.010. Epub 2019 Feb 22. PMID: 30825859.
