EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation.
推荐稀释比 WB:1/1000-1/5000; IHC:P:1/50-1/100; ICC/IF:1/200-1/500; FC:1/20; IP:1/20
Western blot analysis of EGFR in mouse liver lysates using EGFR antibody.
Western blot analysis of EGFR in Hela lysates using EGFR antibody.
Immunocytochemistry analysis of EGFR(green) in Hela using EGFR antibody,and DAPI(blue)
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.