The human BAFF protein, or B-cell activating factor, is a crucial cytokine that plays a significant role in regulating the immune system and promoting B-cell survival and maturation. BAFF is primarily produced by immune cells, including monocytes, macrophages, and dendritic cells. It binds to specific receptors on B cells, allowing their development and preventing apoptosis (cell death). BAFF also influences the production of antibodies and helps regulate the balance of different B-cell subsets.

 

性能参数

Synonyms	BLyS, CD257, TNFSF13B, TNFSF20, TALL-1, BLys, THANK, BAFFB-cell activating factor, ZTNF4
Uniprot No.	Q9Y275
Source	HEK293 cells-derived human BAFF protein, Ala134-Leu285, with N-terminal His tag.
Molecular Weight	Approximately 18.12 kDa.
Purity	> 90% as determined by SDS-PAGE.
Biological Activity	Human BCMA, His tag immobilized on CM5 chip can bind BAFF, His tag, with an affinity constant of 1.55 x 10-9 M as determined in a SPR assay (Biacore 8K).
Endotoxin	< 0.1 EU per 1μg of the protein by the LAL method.
Formulation	Lyophilized from a 0.2 μm filtered concentrated solution in PBS.
Reconstitution	Centrifuge tubes before opening. Dissolve lyophilized protein with PBS. Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

 

储存条件

The product should be stored at -25~-15℃ for 1 year from date of receipt.

2-7 days, 2 ~8 °C under sterile conditions after reconstitution.

3 months, -25~-15℃ under sterile conditions after reconstitution.

 

注意事项

1.Please operate with lab coats and disposable gloves, for your safety.

2.This product is for research use only.

 

产品数据

Ver. CN20230718