DNA repair systems operate in all living cells to manage a variety of DNA lesions. Nucleotide excision repair (NER) is implemented in cases where bulky helix-distorting lesions occur, such as those brought about by UV and certain chemicals. Research studies have shown that expression of ERCC1 is related to survival rate and response to chemotherapeutic drugs in several human cancers including non-small cell lung cancer (NSCLC).

推荐稀释比 WB: 1/500-1/1000  IHC: 1/50-1/100  ICC: 1/100-1/200

Western blot

Western blot analysis of ERCC1 in Hela(WT) and ERCC1-Knockout Hela(KO) using ERCC1 antibody.

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded Human pancreas tissue using ERCC1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunofluorescence

Immunofluorescence analysis of ERCC1 (green) in HeLa using ERCC1 antibody, TRITC-phalloidin (Red) and DAPI (blue).

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