This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
推荐稀释比 IHC: 1/100-1/200 FC: 1/50-1/100 ELISA: 1/10000
Immunohistochemistry
Immunohistochemistry analysis of paraffin-embedded human brain tissues using RBFOX2 antibody.
Flow
Flow Cytometry analysis of Jurkat cells using RBFOX2 antibody (green) and negative control (red).
-15到-25度
