Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.

 

产品性质

别名	H2A.X; H2AFX; H2a/x; HIST5-2AX; Histone H2A.X; gamma H2A.X
SwissProt ID	P16104
基因ID	3014
免疫原	Synthetic phosphopeptide corresponding to residues surrounding Ser139 of human H2A.X.
缓冲液	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
分子量	Calculated MW: 15 kDa; Observed MW: 15 kDa
克隆类型	Monoclonal Antibody
克隆号	2A9
亚型	IgG2a
宿主	Mouse
物种反应	Human,Mouse
推荐应用	WB,ICC/IF
纯化方式	Affinity Purified

 

应用

稀释比 WB: 1/500-1/1000；IF:1/50-1/200；

 

储存条件

-25~-15℃保存

 

注意事项

1. 避免反复冻融。

2. 本产品仅作科研用途。

2. 为了您的安全和健康，请穿实验服并佩戴一次性手套操作。

 

产品数据