The Silent Information Regulator (Sir2) family of genes is a highly conserved group of genes that encode nicotinamide adenine dinucleotide (NAD)-dependent protein deacetylases, also known as class III histone deacetylases. SirT6, a mammalian homolog of Sir2, is a nuclear, chromatin-associated protein that promotes the normal maintenance of genome integrity mediated by the base excision repair (BER) pathway.
产品性质
别名 |
2810449N18Rik; AI043036; Mono ADP ribosyltransferase sirtuin 6; NAD-dependent protein deacetylase sirtuin-6; Regulatory protein SIR2 homolog 6; Regulatory protein SIR2 homolog; SIR2 like 6; SIR2 like protein 6; Sir2 related protein type 6; SIR2-like protein 6; SIR2 |
SwissProt ID |
Q8N6T7 |
基因ID |
51548 |
免疫原 |
Purified recombinant human SIRT6 protein expressed in E.coli. |
缓冲液 |
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
分子量 |
Calculated MW: 39 kDa; Observed MW: 42 kDa |
克隆类型 |
Monoclonal Antibody |
克隆号 |
6C9 |
亚型 |
IgG1 |
宿主 |
Mouse |
物种反应 |
Human,Mouse,Rat,Monkey |
推荐应用 |
WB,ICC/IF,IP |
纯化方式 |
Affinity Purified |
应用
稀释比 WB: 1/500-1/1000;IF:1/50-1/200;IP: 1/20
储存条件
-25~-15℃保存
注意事项
1. 避免反复冻融。
2. 本产品仅作科研用途。
2. 为了您的安全和健康,请穿实验服并佩戴一次性手套操作。
产品数据