Anti-IL-23a Reference Antibody (risankizumab)
产品介绍
Risankizumab (BI 655066) 是一种靶向IL-23 p19亚基的高亲和力人源化IgG单克隆抗体 (Kd < 10 pM)。其通过阻断IL-23的功能，能有效抑制IL-17的产生 (IC50 = 2 pM)。在研究中被应用于多种免疫介导的炎症性疾病研究，如寻常型银屑病、银屑病关节炎、广泛性脓疱型银屑病及红皮病型银屑病。
产品性质
产品特色
应用案例
Purity:SDS-PAGE
Anti-IL-23a Reference Antibody (risankizumab) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
Purity:SEC-HPLC
The purity of Anti-IL-23a Reference Antibody (risankizumab) is 100%, determined by SEC-HPLC.
Bioactivity:ELISA
Immobilized human IL 23P40 His at 2 ug/mL can bind Anti-IL-23a Reference Antibody (risankizumab), EC50=0.04262 ug/mL.
存储条件
-25~-15℃保存，有效期1年。
COA
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