分子生物学
IVD分子诊断
细胞培养与分析
蛋白研究
细胞因子
重组蛋白
抗体
高通量测序建库
病原检测UCF系列
生物医药
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抑制剂激活剂与常用试剂
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耗材
Anti-NKG2A / CD94 Reference Antibody (monalizumab)
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产品介绍

Monalizumab是一种人源化单克隆抗体类免疫检查点抑制剂,其作用靶点为自然杀伤细胞表面受体 NKG2A,通过阻断 NKG2A 介导的抑制性信号,可增强自然杀伤细胞的功能并促进干扰素-γ(IFN-γ)的生成。

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应用案例

Purity:SDS-PAGE

Anti-NKG2A / CD94 Reference Antibody (monalizumab) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 90%.

Purity:SEC-HPLC

The purity of Anti-NKG2A / CD94 Reference Antibody (monalizumab) is more than 95%, determined by SEC-HPLC.

Bioactivity:FACS

Human NKG2A/CD94 HEK293 cells were stained with Anti-NKG2A / CD94 Reference Antibody (monalizumab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50=0.0409 ug/mL.

Function:Blocking

Anti-NKG2A / CD159a Reference Antibody (monalizumab) FACS Blocking was evaluated using human NKG2A/CD94 HEK293 cells. The IC50 was approximately 0.2162 nM.

Function:Luciferase

Anti-NKG2A / CD159a Reference Antibody (monalizumab) Luciferase Assay was evaluated using Human NKG2A/CD94 HEK293. The EC50 was approximately 0.5236 nM.

存储条件

-25~-15℃保存,有效期1年。

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