[ 1 ]Cholesterol promotes EGFR-TKIs resistance in NSCLC by inducing EGFR/Src/Erk/SP1 signaling-mediated ERRα re-expression

[ 2 ]The Ly6ghigh Neutrophil Subset Dictates Breast Cancer Lung Metastasis via CD8+ T Cell Death

[ 3 ]VAMP4/STX8 Mediate the Autophagic Secretion of Mitochondria and Promote TAMs Polarization in HNSCC

[ 4 ]Near infrared enhanced palladium loaded siraitia grosvenorii carbon dots amplify mitophagy for acute lung injury immunotherapy

[ 5 ]SphK1/mitophagy axis in cementocytes drives orthodontic root resorption via mitochondrial transfer to osteoclasts

[ 6 ]Dual-Scale Targeting of Myofibroblasts and Mitochondria via Oral Cascade Delivery Systems Alleviate Intestinal Fibrosis

[ 7 ]Sequentially Targeting Cancer-Associated Fibroblast and Mitochondria Alleviates Tumor Hypoxia and Inhibits Cancer Metastasis by Preventing “Soil” Formation and “Seed” Dissemination

[ 8 ]Mitophagy promotes lung repair and regeneration by restoring epithelial metabolic fitness

[ 9 ]Targeting REV-ERBα/BNIP3 axis attenuates pulmonary arterial hypertension by repressing mitophagy in mice

[ 10 ]Intermediate accumulated upon interruption of fatty acid oxidation flux promotes tumoral ferroptosis and improves immunotherapy

[ 11 ]The gut microbial metabolite trimethylamine N-oxide aggravates GVHD by inducing M1 macrophage polarization in mice

[ 12 ]BNC1 deficiency-triggered ferroptosis through the NF2-YAP pathway induces primary ovarian insufficiency

[ 13 ]A Self-Sustaining Antioxidant Strategy for Effective Treatment of Myocardial Infarction

[ 14 ]A Straw-Reinforced-Clay-Inspired Composite Hydrogel Promotes Diabetic Bone Regeneration via Driving the Immune-Osteogenic Cascade to Remodel Mitochondrial Homeostasis

[ 15 ]GL-V9 disrupts the mitochondrial homeostasis and triggers the integrated stress response by promoting the binding of cytosolic MDM2 with NDUFS1 in colorectal cancer

[ 16 ]CDK9 inhibition blocks the initiation of PINK1-PRKN-mediated mitophagy by regulating the SIRT1-FOXO3-BNIP3 axis and enhances the therapeutic effects involving mitochondrial dysfunction in hepatocellular carcinoma

[ 17 ]ALDOA maintains NLRP3 inflammasome activation by controlling AMPK activation

[ 18 ]Hierarchically Targeted Cu-Doped Carbon Dot/Kynurenic Acid@RM Platform for Restoring Mitochondrial Metabolism and Modulating Inflammation in Acute Pancreatitis

[ 19 ]Overconsumption of fructose aggravates acute GVHD by inducing gut dysbiosis and promoting macrophage-mediated inflammatory response

[ 20 ]Ag2Se quantum dots neurotoxicity: mitochondrial stress drives ferroptosis-dependent microglial inflammation

[ 21 ]Mitochondria-targeting organoselenium theranostic radioprotectors for simultaneous treatment and imaging of radiation-induced liver injury

[ 22 ]The recognition mode between hsRBFA and mitoribosome 12S rRNA during mitoribosomal biogenesis

[ 23 ]Synergistic activation of AMPK by AdipoR1/2 agonist and inhibitor of EDPs–EBP interaction recover NAFLD through enhancing mitochondrial function in mice

[ 24 ]Desuccinylation-Triggered Peptide Self-Assembly: Live Cell Imaging of SIRT5 Activity and Mitochondrial Activity Modulation

[ 25 ]Echinocystic acid inhibits the growth of human bladder cancer cells by suppressing AKT1/GSKβ/β-Catenin signaling and synergizes with gemcitabine

[ 26 ]The E3 ubiquitin ligase NEDD4-1 protects against acetaminophen-induced liver injury by targeting VDAC1 for degradation

[ 27 ]PPARγ preservation via promoter demethylation alleviates osteoarthritis in mice

[ 28 ]ELABELA Targets Mitochondria to Modulate Heart Development

[ 29 ]Brain and Liver Dual-Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy

[ 30 ]A Viscous DES-AAV-Foxo1 Delivery System With High Transfection Efficiency for the Treatment of Corneal Endothelial Dysfunction by Restoring Mitochondria-ER Contacts

[ 31 ]Fungal metabolite-based immunotherapy overcomes tumor-associated macrophage immunosuppression

[ 32 ]Platelet-derived vesicles restore fertility in endometrial injury by modulating the endometrial immune niche in mice

[ 33 ]A novel circular RNA, circIgfbp2, links neural plasticity and anxiety through targeting mitochondrial dysfunction and oxidative stress-induced synapse dysfunction after traumatic brain injury

[ 34 ]Dual Fe2+-clean (DFC) nanotherapeutic system: A precise and synergistic therapy for myocardial ischemia-reperfusion injury via source blockade of mitoNEET

[ 35 ]Mitochondria-targeted salvianolic acid B-Ce nanozyme via intranasal delivery boosts antioxidant and autophagic regulation to alleviate cerebral injury

[ 36 ]Perfluorohexane/hemoglobin nano-oxygen carriers enhance transplanted islet graft survival via hypoxia alleviation and mitochondrial repair

[ 37 ]A superoxide anion-responsive persulfide prodrug for remedying dry eye disease

[ 38 ]Cytosolic escape of mitochondrial DNA triggers cGAS-STING-NLRP3 axis-dependent nucleus pulposus cell pyroptosis

[ 39 ]Mitochondria-targeted supramolecular coordination container encapsulated with exogenous itaconate for synergistic therapy of joint inflammation

[ 40 ]ROS promote hyper-methylation of NDRG2 promoters in a DNMTS-dependent manner: Contributes to the progression of renal fibrosis

[ 41 ]Exercise protects aged mice against coronary endothelial senescence via FUNDC1-dependent mitophagy

[ 42 ]Acetylated tau exacerbates learning and memory impairment by disturbing with mitochondrial homeostasis

[ 43 ]Translocator protein 18 kDa regulates retinal neuron apoptosis and pyroptosis in glaucoma

[ 44 ]β,β-Dimethylacrylshikonin suppresses hepatocellular carcinoma progression through mitochondrial stress and TGM2-associated mitophagy impairment

[ 45 ]METTL3 promotes chemoresistance in small cell lung cancer by inducing mitophagy

[ 46 ]A novel CREB5/TOP1MT axis confers cisplatin resistance through inhibiting mitochondrial apoptosis in head and neck squamous cell carcinoma

[ 47 ]Oxidative Stress Amplifiers as Immunogenic Cell Death Nanoinducers Disrupting Mitochondrial Redox Homeostasis for Cancer Immunotherapy

[ 48 ]Defective mitophagy in aged macrophages promotes mitochondrial DNA cytosolic leakage to activate STING signaling during liver sterile inflammation

[ 49 ]Orchestrating diabetic wound repair via mitochondria-targeted delivery of dihydromyricetin with tailored ADSC-derived biohybrid nanovesicles

[ 50 ]Halting Mitochondrial Domino Effect in Acute Liver Injury: Polyphenol-Sr Nanodrugs Attenuate Cell Death and Sterile Inflammation by Combating ROS Burst and Calcium Overload

[ 51 ]Extracellular Biogenic Nanoscale Mitochondria Reprogram the Wound Microenvironment via ROS Scavenging Independent of Cellular Uptake

[ 52 ]Cationic antimicrobial peptide NRC-03 induces oral squamous cell carcinoma cell apoptosis via CypD-mPTP axis-mediated mitochondrial oxidative stress

[ 53 ]Nrf1 is an indispensable redox-determining factor for mitochondrial homeostasis by integrating multi-hierarchical regulatory networks

[ 54 ]SSBP1 drives high fructose-induced glomerular podocyte ferroptosis via activating DNA-PK/p53 pathway

[ 55 ]AKAP1 contributes to impaired mtDNA replication and mitochondrial dysfunction in podocytes of diabetic kidney disease

[ 56 ]Claudin-10 overexpression suppresses human clear cell renal cell carcinoma growth and metastasis by regulating ATP5O and causing mitochondrial dysfunction

[ 57 ]Graphene oxide disrupted mitochondrial homeostasis through inducing intracellular redox deviation and autophagy-lysosomal network dysfunction in SH-SY5Y cells

[ 58 ]Deep Sc-RNA sequencing decoding the molecular dynamic architecture of the human retina

[ 59 ]Targeted knockdown of Piezo1 in synovial macrophages attenuates osteoarthritis development

[ 60 ]Mitochondrial DNA released from pyroptotic synovial macrophages via DDIT3-mediated mitophagy aggravates osteoarthritis progression

[ 61 ]Targeting C5AR1 disrupts complement-driven G0-phase maintenance and overcomes metabolic drug resistance in glioma

[ 62 ]MTHFD2 modulates neural stem cell proliferation and apoptosis after intracerebral hemorrhage by regulating mitochondrial NADPH homeostasis

[ 63 ]RNA m6A-Regulated circ-ZNF609 Suppression Ameliorates Doxorubicin-Induced Cardiotoxicity by Upregulating FTO

[ 64 ]Mitochondria-associated ER stress evokes immunogenic cell death through the ROS-PERK-eIF2α pathway under PTT/CDT combined therapy

[ 65 ]Osteopontin promotes hepatocellular carcinoma progression through inducing JAK2/STAT3/NOX1-mediated ROS production

[ 66 ]LncRNA ANRIL mediates endothelial dysfunction through BDNF downregulation in chronic kidney disease

[ 67 ]SREBP1-activated lipid metabolism drives ferroptosis and progression of clear cell renal cell carcinoma

[ 68 ]A novel lonidamine derivative targeting mitochondria to eliminate cancer stem cells by blocking glutamine metabolism

[ 69 ]ZNF281 drives hepatocyte senescence in alcoholic liver disease by reducing HK2-stabilized PINK1/Parkin-mediated mitophagy

[ 70 ]RETRACTED: PINK1 deficiency in gastric cancer compromises mitophagy, promotes the Warburg effect, and facilitates M2 polarization of macrophages

[ 71 ]Fructose-coated Angstrom silver inhibits osteosarcoma growth and metastasis via promoting ROS-dependent apoptosis through the alteration of glucose metabolism by inhibiting PDK

[ 72 ]Differential Toxicity of Water-Soluble Versus Water-Insoluble Components of Cowshed PM2.5 on Ovarian Granulosa Cells and the Regulatory Role of Txnip in Overall Toxicity

[ 73 ]Astragalin ameliorates renal injury in diabetic mice by modulating mitochondrial quality control via AMPK-dependent PGC1α pathway

[ 74 ]Spermidine Targets Ovarian Granulosa Cells via Activating the FHC/SLC7A11 Axis to Regulate Iron Homeostasis and Ameliorate Iron Overload-Induced Ovarian Dysfunction

[ 75 ]P4HB UFMylation regulates mitochondrial function and oxidative stress

[ 76 ]Falnidamol and cisplatin combinational treatment inhibits non-small cell lung cancer (NSCLC) by targeting DUSP26-mediated signal pathways

[ 77 ]Protective role of hydrogen sulfide against diabetic cardiomyopathy via alleviating necroptosis

[ 78 ]Lentinan inhibits oxidative stress and alleviates LPS-induced inflammation and apoptosis of BMECs by activating the Nrf2 signaling pathway

[ 79 ]Farnesyl pyrophosphate is a new danger signal inducing acute cell death

[ 80 ](Pro)renin receptor (PRR) exacerbates diabetic cardiomyopathy by suppressing LRRK2-Mediated mitophagy and promoting senescence

[ 81 ]DLAT Sustains Redox Homeostasis and Prevent Colorectal Cancer from Ferroptosis by Regulating SLC25A39-Mediated Mitochondrial Glutathione Transport

[ 82 ]Convergent targeting of FUNDC1-dependent mitophagy sensitises and overcomes resistance to EGFR inhibition

[ 83 ]Qimai Feiluoping decoction inhibits mitochondrial complex I-mediated oxidative stress to ameliorate bleomycin-induced pulmonary fibrosis

[ 84 ]Small molecule-driven SIRT3-autophagy-mediated NLRP3 inflammasome inhibition ameliorates inflammatory crosstalk between macrophages and adipocytes

[ 85 ]The Biphasic Effect of Flavonoids on Oxidative Stress and Cell Proliferation in Breast Cancer Cells

[ 86 ]Collagen Type VI Alpha 1 as a Regulator of Redox Homeostasis in Antioxidant-Enhanced Osteogenesis of Dental Stem Cells

[ 87 ]Induction of ferroptosis in response to graphene quantum dots through mitochondrial oxidative stress in microglia

[ 88 ]Morin enhances the renoprotective effects of Empagliflozin in diabetic kidney disease via targeting ATF6-DAPK1 signaling

[ 89 ]Salidroside facilitates therapeutic angiogenesis in diabetic hindlimb ischemia by inhibiting ferroptosis

[ 90 ]Reversal of Epigenetic Peroxisome Proliferator-Activated Receptor-γ Suppression by Diacerein Alleviates Oxidative Stress and Osteoarthritis in Mice

[ 91 ]Regulatory mechanism of α-hederin upon cisplatin sensibility in NSCLC at safe dose by destroying GSS/GSH/GPX2 axis–mediated glutathione oxidation-reduction system

[ 92 ]Moxibustion delays ovarian aging by regulating mitochondrial biogenesis and improving oocyte quality

[ 93 ]Honokiol prevents chronic cerebral hypoperfusion induced astrocyte A1 polarization to alleviate neurotoxicity by targeting SIRT3-STAT3 axis

[ 94 ]Therapeutic effect of SIRT3 on glucocorticoid-induced osteonecrosis of the femoral head via intracellular oxidative suppression

[ 95 ]Resveratrol and its derivative pterostilbene attenuate oxidative stress-induced intestinal injury by improving mitochondrial redox homeostasis and function via SIRT1 signaling

[ 96 ]The Combination of Rhodosin and MMF Prolongs Cardiac Allograft Survival by Inhibiting DC Maturation by Promoting Mitochondrial Fusion

[ 97 ]Quercetin Protects Ethanol-Induced Hepatocyte Pyroptosis via Scavenging Mitochondrial ROS and Promoting PGC-1α-Regulated Mitochondrial Homeostasis in L02 Cells

[ 98 ]The Imbalance of Mitochondrial Homeostasis of Peripheral Blood-Derived Macrophages Mediated by MAFLD May Impair the Walking Ability of Elderly Patients with Osteopenia

[ 99 ]The Effect of Cutibacterium acnes Infection on Nerve Penetration in the Annulus Fibrosus of Lumbar Intervertebral Discs via Suppressing Oxidative Stress

[ 100 ]Hydrogen Sulfide Suppresses Skin Fibroblast Proliferation via Oxidative Stress Alleviation and Necroptosis Inhibition