推荐应用
LILRB4,also known as CD85k and LIR-5, ILT3, is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of an extracellular domain (ECD) with two Ig-like domains, a transmembrane segment, and a cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM). The mature ECD of human ILT3 shares 44% amino acid identity with mouse ILT3. Alternative splicing of human ILT3 generates an isoform that lacks the first ITIM and a secreted isoform that circulates in the serum of cancer patients. ILT3 is expressed on dendritic cells (DC), monocytes, macrophages, and vascular endothelial cells.
高纯度、高活性、低内毒素、高批间一致性
产品数据
-25 ~ -15℃保存，收到货之后有效期1年。 复溶后， 无菌条件下，-85 ~ -65℃保存，3个月有效期。
【应用方向】免疫检查点核心家族：B7-CD28超家族蛋白
456
2026-04-21
【应用方向】TIM-3：下一代肿瘤免疫检查点治疗的核心靶点
345
2026-04-21
【应用方向】SIRP家族分子详解与产品选择指南
310
2026-04-21
【应用方向】OX40-OX40L共刺激轴的T细胞存活调控
344
2026-04-21
【应用方向】LILRB家族：髓系细胞免疫检查点的研究前沿与产品解决方案
418
2026-04-21
【应用方向】LAG-3（CD223）：T细胞耗竭调控网络的核心节点
360
2026-04-21
【应用方向】B7-H3（CD276）：双重功能免疫检查点的分子特征与科研应用
597
2026-04-20
