产品说明书
FAQ
COA
已发表文献
Mouse Lungkine/CXCL15, also named WECHE, is a member of the ELR motif-containing CXC chemokines. Mouse Lungkine shares 35% aa sequence identity with human ENA-78 and 31% identity with human IL-8. CXCL15 is a novel CXC chemokine that is highly expressed in the adult mouse lung. CXCL15 has suppressive activity on proliferation and expansion of multi-potential, erythroid, granulocyte and macrophage progenitors in S-phase specific manner. Lungkine protein is secreted into bronchoalveolar space and is involved in lung-specific neutrophils trafficking. Lungkine is also chemotactic for bone marrow progenitor cells and modulates hematopoietic cell differentiation.
Product Properties
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Synonyms |
CXCL15, Il8, IL-8, Lungkine, Scyb15, Weche |
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Accession |
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GeneID |
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Source |
E.coli-derived mouse Lungkine/CXCL15 protein, Gln26-Ala167. |
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Molecular Weight |
Approximately 16.4 kDa. |
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AA Sequence |
QELRCLCIQE HSEFIPLKLI KNIMVIFETI YCNRKEVIAV PKNGSMICLD PDAPWVKATV GPITNRFLPE DLKQKEFPPA MKLLYSVEHE KPLYLSFGRP ENKRIFPFPI RETSRHFADL AHNSDRNFLR DSSEVSLTGS DA |
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Tag |
None |
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Physical Appearance |
Sterile Filtered White lyophilized (freeze-dried) powder. |
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Purity |
>95% by SDS-PAGE and HPLC analyses. |
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Biological Activity |
The biological activity determined by a chemotaxis bioassay using human neutrophils is in a concentration of 20-100 ng/mL. Fully biologically active when compared to standard. |
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Endotoxin |
< 1.0 EU per 1μg of the protein by the LAL method. |
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Formulation |
Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4, with 0.02% Tween-20. |
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Reconstitution |
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions. |
Shipping and Storage
The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Cautions
1. Avoid repeated freeze-thaw cycles.
2. For your safety and health, please wear lab coats and disposable gloves for operation.
3. For research use only!
HB220408
