KDM2A/7A-IN-1是选择性KDM2A/7A抑制剂，首创性且细胞通透，对KDM2A的抑制活性IC50=0.16μM，对其他JmjC家族靶点选择性为75倍，对甲基转移酶和组蛋白乙酰转移酶无作用。

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