Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.

推荐稀释比 WB:1/500-1/1000;IF:1/50-1/200;FC:1/50-1/100

Western blot analysis of BACE1 in Hela , SK-N-SH , HepG2 , C6 , PC-12 , PANC-1 , NIH/3T3 lysates using BACE1 antibody.

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.