Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Compared to EZH2-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.

推荐稀释比 WB: 1/500-1/1000  IHC: 1/50-1/100  IF: 1/50-1/200  FC: 1/50-1/100

Western

Western blot analysis of KMT6 / EZH2 in HEK293 lysates using KMT6 antibody.

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded Human tonsil using KMT6 / EZH2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunofluorescence

Immunofluorescence analysis of KMT6 in Hela using KMT6 / EZH2 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。