Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. May play a role in smooth muscle cell contractility.

推荐稀释比 WB: 1/500-1/1000  IP: 1/20  FC: 1/50-1/100

Western

Western blot analysis of HDAC8 in HeLa lysates using HDAC8 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。