推荐应用
Siglec-10 is a ligand for CD52, the target of the therapeutic monoclonal antibody Alemtuzumab. It is also reported to bind to Vascular adhesion protein 1 (VAP-1) and to the co-stimulatory molecule CD24 also known as HSA (Heat-stable antigen).Siglecs (sialic acid binding Ig-like lectins) are I-type lectins that belong to the immunoglobulin superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by a varying number of Ig-like C2-type domains. Siglecs 5-11 constitute the CD33/Siglec-3 related group, and are differentially expressed in the hematopoietic system.
高活性、高纯度、低内毒素、高批间一致性
-25~-15℃保存,收到货之后有效期2年。复溶后, -85~-65℃保存,3个月有效期。
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【应用方向】药靶明星 | FGFRs家族蛋白解析
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【应用方向】解析Fc受体:抗体药物研发的核心靶点与评价基石
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【应用方向】FcγR家族:抗体药物研发的基石与核心靶点
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【技术讲解】ADC药物研究相关靶点汇总
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【应用方向】抗体药筛选的关键—靶点蛋白
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【技术讲解】重要免疫检查点:PD-1及其配体
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【应用方向】药靶明星|FGFs&FGFRs家族蛋白解析
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【应用方向】热门肿瘤靶点蛋白-EGFR表皮生长因子受体
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【技术讲解】双抗热门靶点-双特异性抗体靶点CD3D&CD3E
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