[ 1 ]TRIM27 maintains gut homeostasis by promoting intestinal stem cell self-renewal

[ 2 ]Oral delivery of enterocyte-mimetic butyrate-loaded nanoparticles repairs the gut barrier and inhibits growth of digestive system tumors

[ 3 ]Neuropeptide SP protects against colitis and linked anxiety-like behavior through the putative roles of gut microbiota and metabolite inositol

[ 4 ]A microbiota-IPA axis facilitates intestinal stem cell-mediated regeneration in colitis through a Hopx-associated program

[ 5 ]Engineered exosome nanovesicles for delivery of antibodies to treat inflammatory bowel disease

[ 6 ]Self-adaptive nanozyme-loaded yeast microcapsules for multifunctional and precise therapy of colitis via intestinal microenvironment remodeling

[ 7 ]ZUP1 suppresses ulcerative colitis and colitis-associated colorectal cancer through K63-linked deubiquitination of ERK1/2

[ 8 ]RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

[ 9 ]Remodeling of Capsular Polysaccharide Enhances Colonization and Therapeutic Efficacy of Probiotic Escherichia coli against colitis

[ 10 ]Versatility of bacterial outer membrane vesicles in regulating intestinal homeostasis

[ 11 ]Macrophage membrane-biomimetic cinnamaldehyde nanomedicine ameliorates inflammatory bowel disease by suppressing macrophage M1 polarization

[ 12 ]Improving drug utilization platform with injectable mucoadhesive hydrogel for treating ulcerative colitis

[ 13 ]Structure-dependent effects of yeast- and Gleditsia-derived mannan oligosaccharides on dextran sodium sulfate-induced colitis in mice

[ 14 ]A self-assembled, hydrogel-transformable small-molecule coacervate for multi-mechanistic mucosal repair in ulcerative colitis

[ 15 ]Ultrafast self-healing hyaluronic acid hydrogel for targeted probiotic delivery and ulcerative colitis alleviation

[ 16 ]Portulaca oleracea L. polysaccharide alleviates colitis-associated bone loss through Muribaculaceae-enriched gut microbiota and elevated colonic melatonin

[ 17 ]Fucoidan-Based Hydrogel with Ultrafast Self-Healing Properties for Enhanced Probiotic Delivery to Alleviate Colitis and Microbiota Dysbiosis in Mice

[ 18 ]Palmitic acid activates c-Myc via dual palmitoylation-dependent pathways to promote colon cancer

[ 19 ]Layer-by-layer silk fibroin microparticles for codelivery for treating refractory colonic lesions

[ 20 ]Milk-derived extracellular vesicles alleviate ulcerative colitis by regulating the gut immunity and reshaping the gut microbiota

[ 21 ]Inflammation-responsive framework nucleic acid-enabled effective intestinal accumulation for ulcerative colitis therapy

[ 22 ]Systemic application of IL-33 for cancer immunoprevention and immunotherapy

[ 23 ]Liandan Xiaoyan Formula ameliorates DSS-induced ulcerative colitis through altering the metabolism of bile acids by regulating the FXR-FGF15 signaling pathway

[ 24 ]Polydisperse polystyrene microplastics exacerbate colitis through gut microbiota-butyrate-PPARγ axis disruption in mice

[ 25 ]Mesenchymal Stem Cell Exosomes Encapsulated Oral Microcapsules for Acute Colitis Treatment

[ 26 ]Bigel microspheres encapsulating supramolecular bioactives enabled by electrospraying for colon-targeted delivery and ulcerative colitis therapy

[ 27 ]Few-shot learning-driven discovery of Lutein suppresses Th1-mediated inflammation via glucose metabolism

[ 28 ]Yeast Microcapsule Mediated Natural Products Delivery for Treating Ulcerative Colitis through Anti-Inflammatory and Regulation of Macrophage Polarization

[ 29 ]Discoidin domain receptor 1(DDR1) promote intestinal barrier disruption in Ulcerative Colitis through tight junction proteins degradation and epithelium apoptosis

[ 30 ]Ergothioneine attenuates whole-abdominal irradiation-induced multi-organ injury via the gut-heart-brain axis by modulating calcium voltage-gated channel subunit alpha1 C (Cacna1c) expression

[ 31 ]Orally administrated nucleotide-delivery particles from microfluidics for inflammatory bowel disease treatment

[ 32 ]ROS Scavenging and inflammation-directed polydopamine nanoparticles regulate gut immunity and flora therapy in inflammatory bowel disease

[ 33 ]Oral microbiota affects the efficacy and prognosis of radiotherapy for colorectal cancer in mouse models

[ 34 ]Identification of Immune-Related Gene Signature and Prediction of CeRNA Network in Active Ulcerative Colitis

[ 35 ]A colon-targeted nanozyme-inulin hydrogel system for reactive oxygen species scavenging and gut microbiota modulation in inflammatory bowel disease therapy

[ 36 ]The WNK-OXSR1 osmosensing pathway mediates intestinal regeneration via Hippo-YAP signaling

[ 37 ]Oyster polysaccharides relieve DSS-induced colitis via anti-inflammatory and maintaining the physiological hypoxia

[ 38 ]Gut commensal derived-valeric acid protects against radiation injuries

[ 39 ]Valerylated high-amylose maize starch enabling colon-targeted valerate delivery: Synthesis, characterization, and impact on gut health

[ 40 ]Effect of Extracellular Vesicles Derived From Lactobacillus plantarum Q7 on Gut Microbiota and Ulcerative Colitis in Mice

[ 41 ]Macrophage-derived IL-6 reprograms lipid metabolism to promote colorectal cancer development through USP14-mediated FASN deubiquitination

[ 42 ]Dietary lactate supplementation can alleviate DSS-induced colitis in piglets

[ 43 ]Honokiol Ameliorates DSS-Induced Mouse Colitis by Inhibiting Inflammation and Oxidative Stress and Improving the Intestinal Barrier

[ 44 ]Isosteviol Sodium Ameliorates Dextran Sodium Sulfate-Induced Chronic Colitis through the Regulation of Metabolic Profiling, Macrophage Polarization, and NF-κB Pathway

[ 45 ]Dual-targeted milk exosome-coated probiotics for IBD therapy via ROS scavenging and microbiota modulation

[ 46 ]Qingre Xingyu recipe exerts inhibiting effects on ulcerative colitis development by inhibiting TNFα/NLRP3/Caspase-1/IL-1β pathway and macrophage M1 polarization

[ 47 ]Isosteviol Sodium Exerts Anti-Colitic Effects on BALB/c Mice with Dextran Sodium Sulfate-Induced Colitis Through Metabolic Reprogramming and Immune Response Modulation

[ 48 ]Disulfide Cross-Linked Thiolated Chitosan/Oxidized Dextran–Oleylamine Micelle–Hydrogel System with pH/ROS Dual-Responsive Cascade Drug Release for Integrated Colon Targeting and Mucosal Repair in Inflammatory Bowel Disease

[ 49 ]Loss of p53 exacerbates autoimmunity by reprogramming propionyl-CoA metabolism and histone modifications in Treg cells

[ 50 ]Euphorbia humifusa Willd. alleviates ulcerative colitis by inhibiting lipid peroxidation via ACSL4/COX-2 axis

[ 51 ]Muscone Exerts Rapid Antidepressant Effects Through Modulating Glutamatergic Neural Transmission in the Anterior Cingulate Cortex Against Peripheral Inflammation-induced Depression

[ 52 ]Targeting SLC5A2 suppresses colorectal tumour development by enhancing NK cell activity through extracellular vesicle-dependent MICA/B signalling

[ 53 ]Rational Design, Synthesis, and Biological Evaluation of Potent, Highly Selective 1,2,4-Oxadiazole-Based S1PR1 Agonists for UC Treatment

[ 54 ]Identification of 2,4-Diaminopyrimidine Derivatives as Novel Gut-Restricted Selective JAK1 Inhibitors for the Treatment of Inflammatory Bowel Disease

[ 55 ]The Anti-Inflammatory Effect of Bovine Bone-Gelatin-Derived Peptides in LPS-Induced RAW264.7 Macrophages Cells and Dextran Sulfate Sodium-Induced C57BL/6 Mice

[ 56 ]Angelica oil restores the intestinal barrier function by suppressing S100A8/A9 signalling in mice with ulcerative colitis

[ 57 ]Qingchang Wenzhong Decoction reduce ulcerative colitis in mice by inhibiting Th17 lymphocyte differentiation

[ 58 ]Danthron Attenuates Intestinal Inflammation by Modulating Oxidative Stress via the EGFR-PI3K-AKT and Nrf2-HO-1 Pathways

[ 59 ]Fermented Astragalus and its metabolites regulate inflammatory status and gut microbiota to repair intestinal barrier damage in dextran sulfate sodium-induced ulcerative colitis

[ 60 ]Thyme (Thymus vulgaris L.) polyphenols ameliorate DSS-induced ulcerative colitis of mice by mitigating intestinal barrier damage, regulating gut microbiota, and suppressing TLR4/NF-κB-NLRP3 inflammasome pathways

[ 61 ]Bifidobacterium bifidum relieved DSS-induced colitis in mice potentially by activating the aryl hydrocarbon receptor

[ 62 ]A tetrapeptide from maize combined with probiotics exerted strong anti-inflammatory effects and modulated gut microbiota in DSS-induced colitis mice

[ 63 ]Activation of MTCH2 by Momordin Ic Prevents Colitis and Colitis-Associated Colorectal Cancer Through Rescuing the Mitochondrial Dysfunction of Macrophage

[ 64 ]Integrated RNA-seq and network pharmacology analyses suggest PI3K–Akt and NF-κB pathway modulation in the protective effects of diosmin against experimental colitis

[ 65 ]Inhibition of GABAAR or Application of Lactobacillus casei Zhang Alleviates Ulcerative Colitis in Mice: GABAAR as a Potential Target for Intestinal Epithelial Renewal and Repair

[ 66 ]Wheat Bran Arabinoxylan Potentiates Hepatoprotective Efficacy of Postbiotic Limosilactobacillus reuteri in Colitis Mice via a Gut–Liver Axis

[ 67 ]Licorice flavonoids fermented by a synthetic microbial consortium attenuate DSS-induced ulcerative colitis: efficacy and mechanistic insights

[ 68 ]Probiotic extracellular vesicles from Ligilactobacillus murinus alleviate colonic injury and inflammation via miR-146a-5p-driven macrophage polarization

[ 69 ]DNA methylation-mediated silencing of MEOX1 promotes glycolysis and immune evasion in colorectal cancer cells through inhibition of GLP2R transcription

[ 70 ]Sunite sheep tail fat alleviates ulcerative colitis by regulating intestinal flora and metabolites to activate PPAR signaling pathway

[ 71 ]Constructing Starch-Based Porous Delivery System to Enhance the Stability and Intestinal Absorption Properties of Brown Algal Polyphenols

[ 72 ]Disulfiram-loaded lactoferrin nanoparticles for treating inflammatory diseases

[ 73 ]Tumor-targeting engineered probiotic Escherichia coli Nissle 1917 inhibits colorectal tumorigenesis and modulates gut microbiota homeostasis in mice

[ 74 ]Bifidobacterium and Lactobacillus improve inflammatory bowel disease in zebrafish of different ages by regulating the intestinal mucosal barrier and microbiota

[ 75 ]Bifidobacterium bifidum Ameliorates DSS-Induced Colitis in Mice by Regulating AHR/NRF2/NLRP3 Inflammasome Pathways through Indole-3-lactic Acid Production

[ 76 ]6-Bromoindole-3-acetonitrile Attenuates DSS-Induced Colitis by Inhibiting Epithelial Cell Pyroptosis

[ 77 ]Macrophage-mimetic, glycyrrhizic acid-functionalized liposomes for targeted delivery of celastrol in ulcerative colitis

[ 78 ]Central administration of human opiorphin alleviates dextran sodium sulfate-induced colitis in mice through activation of the endogenous opioid system

[ 79 ]Pharmacokinetic Study of Four Major Bioactive Components of Liandan Xiaoyan Formula in Ulcerative Colitis and Control Rats Using UPLC-MS/MS

[ 80 ]The potential mechanism of huazhuojiedu decoction in the treatment of ulcerative colitis based on network pharmacology and experimental validation

[ 81 ]Berberine-taxifolin co-administration attenuates inflammatory response and intestinal barrier injury via nf-κB/NLRP3 suppression in colitis

[ 82 ]GB20-5A8-31, an anti-TL1A antibody for treating inflammatory bowel disease

[ 83 ]Genome-characterized Lacticaseibacillus rhamnosus Hao9 alleviates DSS–induced chronic low-grade inflammation and modulates the gut microbiota

[ 84 ]Geniposide Ameliorates DSS-Induced Colitis via Synergistically Restoring Intestinal Barrier Integrity and Inhibiting the NF-κB-NLRP3-Pyroptosis Axis

[ 85 ]Safflower Polysaccharide Inhibits AOM/DSS-Induced Mice Colorectal Cancer Through the Regulation of Macrophage Polarization

[ 86 ]Edible Bird’s Nest Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in C57BL/6J Mice by Restoring the Th17/Treg Cell Balance

[ 87 ]Lactobacillus rhamnosus GG Derived Extracellular Vesicles Modulate Gut Microbiota and Attenuate Inflammatory in DSS-Induced Colitis Mice

[ 88 ]Targeted inhibition of FcRn reduces NET formation to ameliorate experimental ulcerative colitis by accelerating ANCA clearance

[ 89 ]High-fructose corn syrup promotes proinflammatory Macrophage activation via ROS-mediated NF-κB signaling and exacerbates colitis in mice

[ 90 ]Apigenin-7-O-glucoside alleviates DSS-induced colitis by improving intestinal barrier function and modulating gut microbiota

[ 91 ]Dioscin modulates macrophages polarization and MDSCs differentiation to inhibit tumorigenesis of colitis-associated colorectal cancer

[ 92 ]An edible hydrogel synthesized by metal-polyphenol and deep eutectic solvent alleviated the DSS-induced murine ulcerative colitis

[ 93 ]Activation of GABABR alleviates DSS-induced colitis in mice by rebalancing inflammatory responses and antioxidant capacity through IRAK-M

[ 94 ]Ethanol extract of Piper wallichii ameliorates DSS-induced ulcerative colitis in mice: Involvement of TLR4/NF-κB/COX-2 signaling pathway

[ 95 ]Casein-fed mice showed faster recovery from DSS-induced colitis than chicken-protein-fed mice

[ 96 ]Immuno-PET Imaging of TNF-α in Colitis Using 89Zr-DFO-infliximab

[ 97 ]WITHDRAWN: Qing-Re-Xing-Yu decoction confers intestinal barrier protection by reducing epithelial cell pyroptosis in experimental ulcerative colitis based on a NLRP3-GSDMD axis-dependent mechanism

[ 98 ]Xuanwei ham derived peptides exert the anti-inflammatory effect in the dextran sulfate sodium-induced C57BL/6 mice model

[ 99 ]Preventive and Therapeutic Spermidine Treatment Attenuates Acute Colitis in Mice

[ 100 ]Polysaccharides from Panax ginseng C. A. Meyer alleviated DSS-induced IBD by inhibiting JAK2/STAT1/NLPR3 inflammasome signalling pathway in mice