[ 1 ]Dual epitope anti-LILRB4 synthetic T-cell receptor and antigen receptor (STAR)-T-cell therapy for relapsed/refractory acute myeloid leukemia

[ 2 ]Efficient and precise programmable DNA knock-in without double-strand breaks

[ 3 ]Tuning the sensitivity of mechanosensory receptors through histidine scanning

[ 4 ]Structural decoding of reversible covalent linkage of odorants in human olfactory receptor OR6A2

[ 5 ]Circ3823 contributes to growth, metastasis and angiogenesis of colorectal cancer: involvement of miR-30c-5p/TCF7 axis

[ 6 ]The Ly6ghigh Neutrophil Subset Dictates Breast Cancer Lung Metastasis via CD8+ T Cell Death

[ 7 ]The type-I interferon priming signal balances antibacterial and antitumor trained immunity in alveolar macrophages

[ 8 ]An SLCO2B1 mRNA Isoform Acts as a Noncoding RNA to Drive Cancer Progression by Triggering Protein Biosynthesis

[ 9 ]A viral protein orchestrates rice ethylene signaling to coordinate viral infection and insect vector-mediated transmission

[ 10 ]mRNA Vaccines Against SARS-CoV-2 Variants Delivered by Lipid Nanoparticles Based on Novel Ionizable Lipids

[ 11 ]Lycium Barbarum Polysaccharide-based Hydrogel as a Novel Oral Colon-Targeted Drug Delivery System for Enhanced MSS-CRC Treatment by Macrophage Lipid Reprogramming

[ 12 ]Targeting FAPα-expressing hepatic stellate cells overcomes resistance to antiangiogenics in colorectal cancer liver metastasis models

[ 13 ]Simultaneous Deep Tracking of Stem Cells by Surface Enhanced Raman Imaging Combined with Single-Cell Tracking by NIR-II Imaging in Myocardial Infarction

[ 14 ]BCAT1 inhibits crotonate-related epigenetic modulation of metabolic genes in tumor-associated macrophages to counter immunosuppression

[ 15 ]Microalgae-based oral microcarriers for gut microbiota homeostasis and intestinal protection in cancer radiotherapy

[ 16 ]Co-expression of a PD-L1-specific chimeric switch receptor augments the efficacy and persistence of CAR T cells via the CD70-CD27 axis

[ 17 ]CRISPR/Cas9 Screens Reveal that Hexokinase 2 Enhances Cancer Stemness and Tumorigenicity by Activating the ACSL4-Fatty Acid β-Oxidation Pathway

[ 18 ]Dynamic Adjust of Non-Radiative and Radiative Attenuation of AIE Molecules Reinforces NIR-II Imaging Mediated Photothermal Therapy and Immunotherapy

[ 19 ]Functional xenogeneic hematopoietic cells maintaining donor-dominant identity and immune tolerance enable therapy

[ 20 ]Enhancement of T cell infiltration via tumor-targeted Th9 cell delivery improves the efficacy of antitumor immunotherapy of solid tumors

[ 21 ]Anesthetic Propofol Promotes Tumor Metastasis in Lungs via GABAAR-Dependent TRIM21 Modulation of Src Expression

[ 22 ]Integrative proteomic characterization of adenocarcinoma of esophagogastric junction

[ 23 ]μ-opioid receptor agonist facilitates circulating tumor cell formation in bladder cancer via the MOR/AKT/Slug pathway: a comprehensive study including randomized controlled trial

[ 24 ]Phototheranostic nanoparticles with aggregation-induced emission as a four-modal imaging platform for image-guided photothermal therapy and ferroptosis of tumor cells

[ 25 ]LILRB3 inhibition reverses immunosuppression in glioma: a nanoparticle-based therapeutic strategy

[ 26 ]Reversing the PAI-1-induced fibrotic immune exclusion of solid tumor by multivalent CXCR4 antagonistic nano-permeator

[ 27 ]Gli1 promotes epithelial–mesenchymal transition and metastasis of non-small cell lung carcinoma by regulating snail transcriptional activity and stability

[ 28 ]Coupling proteostasis and de novo purine biosynthesis of PSMD14 fuels glioblastoma progression and chemoresistance

[ 29 ]Targeting FAPα-positive hepatic stellate cells ameliorates the formation of pre-metastatic niche

[ 30 ]GNL3 Orchestrates AR Transcriptional Programs to Drive Castration-Resistant Prostate Cancer and Immune Evasion

[ 31 ]Phase Separation-Mediated SRF/P54nrb Transcription Complex Shapes the Vasculature Microenvironment via Upregulating OLFML3 in Glioblastoma

[ 32 ]Engineered Bacteria-Vesicle Delivered Lactate Reprogramming Boosts Tumor Radiosensitivity

[ 33 ]COST1 stimulates RHD3 GTPase activity to maintain ER morphology and plant growth in Arabidopsis

[ 34 ]HSP90.2 promotes CO2 assimilation rate, grain weight and yield in wheat

[ 35 ]The protein phosphatase OsPP1a dephosphorylates and stabilizes CatC to scavenge excess H2O2 and enhance salt tolerance in rice

[ 36 ]Functional evolution and rewiring of the UVR8-BES1/BIM1 module underpin the refined UV-B responses during plant terrestrialization

[ 37 ]Targeting the C/EBPβ-PRAME-EZH2 complex modulates the Netrin-4/AKT axis to inhibit renal cancer tumorigenesis and metastasis

[ 38 ]The transcription factors RIN and NOR have both redundant and specific roles in the initiation and progression of fruit ripening

[ 39 ]An apoplastic Lasiodiplodia theobromae effector triggers plant immunity through a lectin receptor-like kinase in peach

[ 40 ]Mesenchymal stem cells encapsulated in a reactive oxygen species-scavenging and O2-generating injectable hydrogel for myocardial infarction treatment

[ 41 ]Hydrogen sulfide-linked persulfidation of ABI4 controls ABA responses through the transactivation of MAPKKK18 in Arabidopsis

[ 42 ]FERONIA regulates plant thermomorphogenesis via nuclear translocation and auxin pathway modulation

[ 43 ]Biocompatible therapeutic albumin/genipin bioglue for postoperative wound adhesion and residual tumor ablation

[ 44 ]Dual-adjuvanted GPC3 mRNA vaccine delivered by lipid nanoparticles for hepatocellular carcinoma immunotherapy

[ 45 ]Intravitreal delivery of LATS1 mRNA by lipid nanoparticles as an effective strategy for uveal melanoma therapy

[ 46 ]Melanoma exosomal miR-708-5p promotes macrophage M2 polarization and cancer metastasis

[ 47 ]EGFR-dependent delivery of phosphorylated IGFBP3 by cancer stem cells drives chemotherapy resistance in colorectal cancer

[ 48 ]CAF-derived exosomal circMPP6 drives ovarian cancer metastasis by coordinating nuclear and cytoplasmic regulation of ADAM22 to activate TGF-β/Smad signaling

[ 49 ]HFB301001, an OX40-based immunotherapy, drives Treg clearance and CTL activation through optimized OX40 receptor clustering

[ 50 ]GLUT3 drives paclitaxel resistance in peritoneal metastatic gastric cancer by promoting H3K18 lactylation-mediated MAPKAP1 transcription to suppress ferroptosis

[ 51 ]A dual role of human tRNA methyltransferase hTrmt13 in regulating translation and transcription

[ 52 ]Potential of peptide-engineered exosomes with overexpressed miR-92b-3p in anti-angiogenic therapy of ovarian cancer

[ 53 ]FTO promotes multiple myeloma progression by posttranscriptional activation of HSF1 in an m6A-YTHDF2-dependent manner

[ 54 ]Blue light-dependent interactions of CRY1 with GID1 and DELLA proteins regulate gibberellin signaling and photomorphogenesis in Arabidopsis

[ 55 ]Arabidopsis cryptochrome 1 controls photomorphogenesis through regulation of H2A.Z deposition

[ 56 ]LncRNA SPOCD1-AS from ovarian cancer extracellular vesicles remodels mesothelial cells to promote peritoneal metastasis via interacting with G3BP1

[ 57 ]A nanodrug combining CD47 and sonodynamic therapy efficiently inhibits osteosarcoma deterioration

[ 58 ]Decrease of circARID1A retards glioblastoma invasion by modulating miR-370-3p/ TGFBR2 pathway

[ 59 ]LncRNA Neat1 promotes the macrophage inflammatory response and acts as a therapeutic target in titanium particle-induced osteolysis

[ 60 ]A multifunctional non-viral vector for the delivery of MTH1-targeted CRISPR/Cas9 system for non-small cell lung cancer therapy

[ 61 ]The combination of gemcitabine and ginsenoside Rh2 enhances the immune function of dendritic cells against pancreatic cancer via the CARD9-BCL10-MALT1 / NF-κB pathway

[ 62 ]m6A modification confers thermal vulnerability to HPV E7 oncotranscripts via reverse regulation of its reader protein IGF2BP1 upon heat stress

[ 63 ]Targeting GPA33 with CAR-macrophages: a novel immunotherapeutic approach for colorectal cancer

[ 64 ]Mitochondrial LINC00942 activates complex I and inhibits ferroptosis through interacting with GRSF1 in liver cancer

[ 65 ]Enhance anti-lung tumor efficacy of chimeric antigen receptor-T cells by ectopic expression of C–C motif chemokine receptor 6

[ 66 ]GRP75-driven, cell-cycle-dependent macropinocytosis of Tat/pDNA-Ca2+ nanoparticles underlies distinct gene therapy effect in ovarian cancer

[ 67 ]FcMAPK4-phosphorylated FcNOR activates FcERF5 to promote fig fruit softening through activation of FcPG12 expression

[ 68 ]Metabolic modulation of CtBP dimeric status impacts the repression of DNA damage repair genes and the platinum sensitivity of ovarian cancer

[ 69 ]Rubber tree iron superoxide dismutase gene HbFSD1 is positively regulated by the basic leucine zipper transcription factor HbbZIP37 and enhances drought tolerance in transgenic Arabidopsis

[ 70 ]Modulation of oxidative phosphorylation augments antineoplastic activity of mitotic aurora kinase inhibition

[ 71 ]Prrx1 promotes stemness and angiogenesis via activating TGF-β/smad pathway and upregulating proangiogenic factors in glioma

[ 72 ]Conservation and divergence of UVR8 photoreceptor-mediated UV-B signaling in Marchantia polymorpha

[ 73 ]NAD+ supplementation limits triple-negative breast cancer metastasis via SIRT1-P66Shc signaling

[ 74 ]A FERONIA–MPK3/6–WRKY3/4 module links auxin signaling to lateral root development in Arabidopsis

[ 75 ]Meloxicam-1-d-MT Dual-Drug Hydrogel Serves as an Immunomodulator to Reverse Tumor Postoperative Recurrence and Metastasis

[ 76 ]Circular RNA hsa_circ_0008305 (circPTK2) inhibits TGF-β-induced epithelial-mesenchymal transition and metastasis by controlling TIF1γ in non-small cell lung cancer

[ 77 ]The tomato methyl-CpG-binding domain SlMBD5 promotes seed germination by repressing the gibberellin catabolism gene SlGA2ox4

[ 78 ]Low expression levels of the conserved nuclear histone acetyltransferase 1 restrict virus infection in plants

[ 79 ]DHODH is a synthetic lethal target in PIK3CA-mutant colorectal cancer

[ 80 ]Circular RNA hsa-circ-0001030 suppresses proliferation and cisplatin tolerance in TSCC via interaction with PKM2

[ 81 ]TNF-α/IL-1β-licensed hADSCs alleviate cholestatic liver injury and fibrosis in mice via COX-2/PGE2 pathway

[ 82 ]Transcription factors GmERF1 and GmWRKY6 synergistically regulate low phosphorus tolerance in soybean

[ 83 ]Engineering Synthetic CopT/A-Based Genetic Biosensors for miRNA Imaging and Functional Gene Regulation

[ 84 ]Injectable nanostructured colloidal gels resembling native nucleus pulposus as carriers of mesenchymal stem cells for the repair of degenerated intervertebral discs

[ 85 ]HSP90.2 modulates 2Q2-mediated wheat resistance against powdery mildew

[ 86 ]SM22α+ vascular mural cells are essential for vessel stability in tumors and undergo phenotype transition regulated by Notch signaling

[ 87 ]Arabidopsis cryptochrome 1 promotes stomatal development through repression of AGB1 inhibition of SPEECHLESS DNA-binding activity

[ 88 ]RETRACTED: lncRNA lnc-TSI Inhibits Metastasis of Clear Cell Renal Cell Carcinoma by Suppressing TGF-β-Induced Epithelial-Mesenchymal Transition

[ 89 ]Natural variation in TaRFR1-5B modulates Fusarium head blight resistance via recognition of pTaRIN1-like in wheat

[ 90 ]Identification and characterization of cotton PHYTOCHROME-INTERACTING FACTORS in temperature-dependent flowering

[ 91 ]Photoexcited Cryptochrome2 Interacts Directly with TOE1 and TOE2 in Flowering Regulation

[ 92 ]Light-Induced Basic/Helix-Loop-Helix64 Enhances Anthocyanin Biosynthesis and Undergoes CONSTITUTIVELY PHOTOMORPHOGENIC1-Mediated Degradation in Pear

[ 93 ]Biocompatible nanomicelles for sensitive detection and photodynamic therapy of early-stage cancer

[ 94 ]CircGLIS3 Promotes High-Grade Glioma Invasion via Modulating Ezrin Phosphorylation

[ 95 ]Genome-Wide Analysis of the Gene Structure, Expression and Protein Interactions of the Peach (Prunus persica) TIFY Gene Family

[ 96 ]Bufalin exacerbates Photodynamic therapy of colorectal cancer by targeting SRC-3/HIF-1α pathway

[ 97 ]Excipient-free nanodispersion of 7-ethyl-10-hydroxycamptothecin exerts potent therapeutic effects against pancreatic cancer cell lines and patient-derived xenografts

[ 98 ]Efficient delivery of VEGF-A mRNA for promoting diabetic wound healing via ionizable lipid nanoparticles

[ 99 ]OLMALINC/OCT4/BMP2 axis enhances osteogenic-like phenotype of renal interstitial fibroblasts to participate in Randall’s plaque formation

[ 100 ]BMP-2 and VEGF-A modRNAs in collagen scaffold synergistically drive bone repair through osteogenic and angiogenic pathways