重组人IgE蛋白(His-Avi标记) Human IgE Protein（94319ES）

Immunoglobulin E (IgE) is well known for its role in allergic disease, the manifestations of which are mediated through its two Fc receptors, FcεRI and CD23 (FcεRII). IgE and its interactions with these receptors are therefore potential targets for therapeutic intervention, and exciting progress has been made in this direction. Furthermore, recent structural studies of IgE-Fc, the two receptors, and of their complexes, have revealed a remarkable degree of plasticity at the IgE-CD23 interface and an even more remarkable degree of dynamic flexibility within the IgE molecule.

高纯度、高活性、低内毒素、高批间一致性

        SDS-PAGE

Human IgE on Bis-Tris PAGE under reduced condition. The purity is greater than 90%.

      SEC-HPLC

The purity of Human IgE is greater than 90% as determined by SEC-HPLC.

ELISA Data

Immobilized Human Fc epsilon RI alpha, hFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Human IgE, His Tag with the EC50 of 1.5ng/ml determined by ELISA.

Immobilized Human IgE, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Omalizumab, hFc Tag with the EC50 of 5.1ng/ml determined by ELISA.

-25 ~ -15℃保存，收到货之后有效期1年。
复溶后， 无菌条件下，-85 ~ -65℃保存，3个月有效期。