Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca²⁺/calmodulin dependent protein kinase II.

 

产品性质

别名	PP1A; PP1A_HUMAN; PP1alpha; PP2C ALPHA; PP2CA; Ppp1ca
SwissProt ID	P62136
基因ID	5499
免疫原	Purified recombinant human PPP1A protein fragments expressed in E.coli.
缓冲液	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
分子量	Calculated MW: 38 kDa; Observed MW: 38 kDa.
克隆类型	Monoclonal Antibody
亚型	IgG1
克隆号	1C11
宿主	Mouse
物种反应	Human
推荐应用	WB, IHC-F, IHC-P, ICC/IF
纯化方式	Affinity Purified

 

应用

稀释比 WB:1/500-1/1000; IHC: 1/50-1/100; IF:1/50-1/200

 

储存条件

-25~-15℃保存

 

注意事项

1. 避免反复冻融。

2. 本产品仅作科研用途。

3. 为了您的安全和健康，请穿实验服并佩戴一次性手套操作。

 

产品数据

Western blot

Western blot analysis of PPP1A in A431, Jurkat and HeLa whole lysates using PPP1A antibody.

 

Immunocytochemistry

Immunocytochemistry analysis of PP1C alpha in HeLa using PPP1A antibody.

 

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded Human breast cancer using PPP1A antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

 

Ver.CN20231220