CD22, a molecule belonging to the SIGLEC family of lectins, is a B-cell restricted glycoprotein that is expressed in the cytoplasm of progenitor B and pre-B cells and on the surface of mature B cells. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signaling.
性能参数
Synonyms |
CD22 molecule; CD22; Siglec-2; B-cell receptor CD22; BL-CAM; SIGLEC2; SIGLEC2FLJ22814 |
Uniprot No. |
P20273-1 |
Source |
Recombinant Human Siglec-2/CD22 Protein is expressed from HEK293 cells with hFc tag at the C-terminal. It contains Asp20-Arg687. |
Molecular Weight |
The protein has a predicted MW of 101.9 kDa. Due to glycosylation, the protein migrates to 120-130 kDa based on SDS-PAGE result. |
Purity |
> 95% as determined by SDS-PAGE and HPLC. |
Endotoxin |
<1.0 EU per 1μg of the protein by the LAL method. |
Formulation |
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge tubes before opening. Dissolve lyophilized protein with sterile water to ensure the concentration is greater than 100 µg/mL. |
储存条件
The product should be stored at -25~-15℃ for 1 year from date of receipt.
2-7 days, 2 ~8 °C under sterile conditions after reconstitution.
3 months, -25~-15℃ under sterile conditions after reconstitution.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
注意事项
1.Please operate with lab coats and disposable gloves,for your safety.
2.This product is for research use only.
产品数据
Ver. CN20230421