CEP-1347是一种通过抑制MLK家族成员来阻断JNK/SAPK通路的抑制剂，具有神经保护作用。此外，它还能作为MDM4抑制剂，并更有效地抑制表达野生型p53的胶质瘤细胞生长。

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-25~-15℃避光保存，有效期3年。

[1] Mitobe Y, Suzuki S, Nakagawa-Saito Y, Togashi K, Sugai A, Sonoda Y, Kitanaka C, Okada M. The Novel MDM4 Inhibitor CEP-1347 Activates the p53 Pathway and Blocks Malignant Meningioma Growth In Vitro and In Vivo. Biomedicines. 2023 Jul 12;11(7):1967. doi: 10.3390/biomedicines11071967. PMID: 37509605; PMCID: PMC10377688.

[2] Wagner AC, Mazzucchelli L, Miller M, Camoratto AM, Göke B. CEP-1347 inhibits caerulein-induced rat pancreatic JNK activation and ameliorates caerulein pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2000 Jan;278(1):G165-72. doi: 10.1152/ajpgi.2000.278.1.G165. PMID: 10644575.