This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100

Western blot analysis of SIGMAR1 in mouse liver and brain lysates, 293T, A549, A431 and PC-3 lysates using SIGMAR1 antibody.

Immunohistochemistry analysis of paraffin-embedded Human liver cancer using SIGMAR1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。